Postoperative Effects of Propofol Versus Sevoflurane Anesthesia
NCT ID: NCT05935930
Last Updated: 2025-02-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
44 participants
INTERVENTIONAL
2021-12-01
2024-12-15
Brief Summary
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Objectives: To compare the efficacy and safety of propofol versus sevoflurane in patients undergoing elective, non-cardiac operations under general anesthesia.
Methods: This was a randomized (1:1), parallel, phase four clinical trial; carried out on 44 patients, who were candidates for elective, non-cardiac operations under general anesthesia at our hospital. Patients were randomly allocated into two equal groups in which anesthesia was maintained with propofol infusion in group P and sevoflurane inhalation in group S.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
TRIPLE
Study Groups
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Group P (n=22)
Propofol group
Propofol 10 MG/ML Injection
Propofol infusion
Group S (n=22)
Sevoflurane group
Sevoflurane Inhalation Liquid
Sevoflurane inhalation
Interventions
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Propofol 10 MG/ML Injection
Propofol infusion
Sevoflurane Inhalation Liquid
Sevoflurane inhalation
Eligibility Criteria
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Inclusion Criteria
* Age from 21 years
* Body Mass Index (BMI) 25-35 kg/m2
Exclusion Criteria
* Age \< 21 years
* Patients with Montreal Objective Cognitive Assessment (MoCA-B) score \< 24 points
* Patients with significant cardiovascular, cerebrovascular, respiratory, liver, renal, endocrine, blood, or immune diseases
* Patients with visual or auditory disease, infection, chronic inflammation, disturbance of consciousness, cognitive impairment, or dementia
* Patients on long-term use of sedatives or steroids, alcohol or drug abuse
* Allergy to any of the study drugs
21 Years
ALL
No
Sponsors
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Damanhour Teaching Hospital
OTHER_GOV
Responsible Party
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Principal Investigators
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Ahmed M Shaat, MD
Role: PRINCIPAL_INVESTIGATOR
Damanhour Teaching Hospital
Locations
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Damanhour Teaching Hospital
Damanhūr, El-Beheira, Egypt
Countries
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Other Identifiers
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DTH: 22004
Identifier Type: -
Identifier Source: org_study_id
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