Comparison of Two Different Intraocular Lenses Implanted With Yamane Technique

NCT ID: NCT05912829

Last Updated: 2023-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2025-05-31

Brief Summary

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In case of instability or rupture of capsular bag occurs during cataract surgery, Yamane technique is one of the options to fix intracocularlens' haptics. Yamane technique uses a double-needle technique that seamlessly fixes the haptics intrascleral by creating a scleral tunnel.

Aberrations, IOL tilting or even dislocations might occur and influence the final outcome of IOL implantation.

The aim of this study is the evaluation of the postoperative tilt of Kowa PU6AS using Yamane technique. Furthermore of the corrected and uncorrected visual acuity and the anterior chamber depth are being developed.

Detailed Description

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During uncomplicated cataract surgery, an intraocular lens (IOL) is implanted into the patient's capsular bag. If increased instability or rupture of this capsular bag occurs due to aggravated intraoperative conditions or IOL dislocation, several options are available to the surgeon to correct the aphakia, all characterized by their respective advantages and disadvantages, but with no clear superiority of any one method.

The popular Yamane technique, or "flanged IOL fixation", uses a double-needle technique that seamlessly fixes the haptics intrascleral by creating a scleral tunnel using two 30-gauge needles.

Examples of lenses used for this purpose are the TECNIS ZA9003 (Johnson\&Johnson, USA) and the Kowa PU6AS (Kowa, Japan). Another approach is the Carlevale FIL-SSF IOL (Soleko, Italy), which was developed specifically for use in aphakia with lack of capsular stability.

All types of implantation are not immune to aberrations, tilting or even dislocation. Many factors influence the final outcome of IOL implantation, be it the optimal choice of intraocular lens power, the surgeon's experience regarding fixation in more challenging eyes, or individual anatomical conditions. As part of quality assurance, an evaluation of monthly and six-monthly data will now be performed. The aim of this study is the evaluation of the postoperative tilt of the Kowa PU6AS in Yamane technique, as well as the evaluation of the corrected and uncorrected visual acuity and the anterior chamber depth within the clinical quality management.

Conditions

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Secondary Cataract Surgery Aphakia Complicated Cataract Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Kowa Group

Patients who had a Kowa lens implanted using the Yamane technique

IOL Master 700

Intervention Type DEVICE

Biometry using the IOL Master 700

Casia-2

Intervention Type DEVICE

Anterior segment-OCT to evaluate lens tilt

MS-39

Intervention Type DEVICE

Corneal Topography using the MS-39

OSIRIS

Intervention Type DEVICE

Abberometry using the OSIRIS-Abberometer

Autorefractor

Intervention Type DEVICE

Evaluation of Refraction using an Autorefractor

Subjective Refraction

Intervention Type DIAGNOSTIC_TEST

Refraction performed by experienced staff

Biomicroscopy

Intervention Type DIAGNOSTIC_TEST

Slit Lamp Examination

Johnson

Patients who had the ZA9003 (J\&J) lens implanted using the Yamane technique

IOL Master 700

Intervention Type DEVICE

Biometry using the IOL Master 700

Casia-2

Intervention Type DEVICE

Anterior segment-OCT to evaluate lens tilt

MS-39

Intervention Type DEVICE

Corneal Topography using the MS-39

OSIRIS

Intervention Type DEVICE

Abberometry using the OSIRIS-Abberometer

Autorefractor

Intervention Type DEVICE

Evaluation of Refraction using an Autorefractor

Subjective Refraction

Intervention Type DIAGNOSTIC_TEST

Refraction performed by experienced staff

Biomicroscopy

Intervention Type DIAGNOSTIC_TEST

Slit Lamp Examination

Interventions

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IOL Master 700

Biometry using the IOL Master 700

Intervention Type DEVICE

Casia-2

Anterior segment-OCT to evaluate lens tilt

Intervention Type DEVICE

MS-39

Corneal Topography using the MS-39

Intervention Type DEVICE

OSIRIS

Abberometry using the OSIRIS-Abberometer

Intervention Type DEVICE

Autorefractor

Evaluation of Refraction using an Autorefractor

Intervention Type DEVICE

Subjective Refraction

Refraction performed by experienced staff

Intervention Type DIAGNOSTIC_TEST

Biomicroscopy

Slit Lamp Examination

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Minimum age: 21 Years
* planned or performed lens implantation using the Kowa PU6AS or the Johnson \& Johnson ZA9003 using the Yamane technique
* signed patient consent form

Exclusion Criteria

* best corrected visual acuity \>0.1 (Snellen)
* pregnancy
Minimum Eligible Age

21 Years

Maximum Eligible Age

110 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johannes Kepler University of Linz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Matthias Bolz, MD

Role: STUDY_CHAIR

JKU Linz

Locations

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Department for Ophthalmology and Optometry, Kepler University Hospital GmbH, Johannes Kepler University Linz

Linz, Upper Austria, Austria

Site Status RECRUITING

Department for Ophthalmology and Optometry

Linz, Upper Austria, Austria

Site Status RECRUITING

Countries

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Austria

Central Contacts

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Christina Silber, MSc

Role: CONTACT

+43 5 7680 83 ext. 1944

Nino Hirnschall, MD

Role: CONTACT

+43 5 7680 83 ext. 73425

Facility Contacts

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Christina Silber, MSc

Role: primary

+4357680831944

Nino Hirnschall, MD

Role: backup

+435768083 ext. 73425

Kepler University Hospital GmbH, Johannes Kepler University

Role: primary

+43 5 7680 83 1944

Other Identifiers

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KUK-Ophthalmology-012

Identifier Type: -

Identifier Source: org_study_id

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