Performance of Two Sclera Fixated Intraocular Lens Concepts

NCT ID: NCT05779306

Last Updated: 2024-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

26 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-19

Study Completion Date

2024-01-30

Brief Summary

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To evaluate and compare the post-operative outcome of two different sceral fixated IOL concepts, the Yamane method (ZA9003, J\&J, USA) and the Carlevale IOL (FIL-SSF, Soleko, Italy).

Detailed Description

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Various approaches to fix the haptics in the sclera can be found in literature. A distinction can be made between suture-fixed and sutureless techniques. The former often proves to be technically challenging and complicated, which has led to an increased rethinking towards sutureless implantation in recent years.

The popular Yamane technique or "flanged IOL fixation" uses a double-needle technique that creates a scleral tunnel and fixates the haptics seamlessly using two 30-gauge needles. However, the haptics must be bent for this purpose Thus, this method is not ideal, since besides from the high degree of manipulation necessary for implantation of the IOL, it is also prone to dislocation and tilt.

A more recent approach is the Carlevale FIL-SSF IOL (Soleko, Italy), which was developed specifically for use in aphakia with a lack of capsular stability. Using two t-shaped anchors, the lens is positioned in two scleral flaps at 180 degrees to each other, without the preparation of a tunnel or excessive manipulation of the haptics. These two self-blocking anchors also provide a great deal of stability. The extent of abberations is also much less with this type of lens implantation, as the fixed position reduces the risk of them. Thus, the Carlevale technique represents a new, potentially superior option for intrascleral fixation.

However, all these types of implantation are not free from aberrations, tilt, or even dislocation. Many factors influence the outcome of IOL implantation, the optimal choice of intraocular lens power, the surgeon's experience regarding fixation in more challenging eyes, or individual anatomical conditions. As part of quality management, an evaluation of monthly and six-monthly data will be performed. The aim of this study is the evaluation of the postoperative tilt of the Carlevale lens, as well as the evaluation of the corrected and uncorrected visual acuity and the anterior chamber depth within the clinical quality management. Patients who have already undergone surgery are called to our clinic by telephone at the earliest 6 weeks after surgery for a one-time follow-up appointment.

The collected data is then evaluated and analyzed as well as compared to the Yamane data.

Conditions

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Cataract Complicated Cataract Complications Operations

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Carlevale

Patients who had a Carlevale lens implanted

IOL Master 700

Intervention Type DEVICE

Biometry using the IOL Master 700

Casia-2

Intervention Type DEVICE

Anterior segment-OCT to evaluate lens tilt

MS-39

Intervention Type DEVICE

Corneal Topography using the MS-39

OSIRIS

Intervention Type DEVICE

Abberometry using the OSIRIS-Abberometer

Autorefractor

Intervention Type DEVICE

Evaluation of Refraction using an Autorefractor

Subjective Refraction

Intervention Type DIAGNOSTIC_TEST

Refraction performed by experienced staff

Yamane

Patients who had a lens implanted using Yamane technique

IOL Master 700

Intervention Type DEVICE

Biometry using the IOL Master 700

Casia-2

Intervention Type DEVICE

Anterior segment-OCT to evaluate lens tilt

MS-39

Intervention Type DEVICE

Corneal Topography using the MS-39

OSIRIS

Intervention Type DEVICE

Abberometry using the OSIRIS-Abberometer

Autorefractor

Intervention Type DEVICE

Evaluation of Refraction using an Autorefractor

Subjective Refraction

Intervention Type DIAGNOSTIC_TEST

Refraction performed by experienced staff

Interventions

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IOL Master 700

Biometry using the IOL Master 700

Intervention Type DEVICE

Casia-2

Anterior segment-OCT to evaluate lens tilt

Intervention Type DEVICE

MS-39

Corneal Topography using the MS-39

Intervention Type DEVICE

OSIRIS

Abberometry using the OSIRIS-Abberometer

Intervention Type DEVICE

Autorefractor

Evaluation of Refraction using an Autorefractor

Intervention Type DEVICE

Subjective Refraction

Refraction performed by experienced staff

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* minimum age of 21 years
* planned surgery or already taken place surgery using a scleral fixated lens

Exclusion Criteria

* best corrected visual acuity \<0.05 Snellen
* pregnancy
* missing informed consent form
Minimum Eligible Age

21 Years

Maximum Eligible Age

110 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Johannes Kepler University of Linz

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nino Hirnschall, MD

Role: PRINCIPAL_INVESTIGATOR

Johannes Kepler University

Locations

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Department for Ophthalmology and Optometry, Kepler University Hospital GmbH, Johannes Kepler University Linz, Altenberger Strasse 69, 4040 Linz, Austria

Linz, Upper Austria, Austria

Site Status

Countries

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Austria

Other Identifiers

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KUK-Ophthalmology-011

Identifier Type: -

Identifier Source: org_study_id

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