Efficacy of Multi-waved Locked System Laser Versus Cold Compression Therapy on Breast Cancer-related Lymphoedema

NCT ID: NCT05911854

Last Updated: 2023-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-21

Study Completion Date

2023-06-05

Brief Summary

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This study was conducted:

* To investigate the effect of MLS Laser in the management of patients with unilateral BCRL regarding lymphatic flow, volumetric measurement and HRQL assessment.
* To investigate the effect of CCT in the management of patients with unilateral BCRL regarding lymphatic flow, volumetric measurement and HRQL assessment.
* To compare the effect of MLS Laser versus CCT in the management of patients with unilateral BCRL regarding lymphatic flow, volumetric measurement and HRQL assessment.

Detailed Description

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Conditions

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Lymphedema

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Study group (A) Multi-waved Locked System Laser group

Group Type EXPERIMENTAL

Multi-waved Locked System Laser

Intervention Type DEVICE

The M6 therapy laser is a robotized multi-target device designed to treat patients suffering pathologies affecting a wide area, and to perform automatic applications.

complete decongestive therapy

Intervention Type OTHER

Complete decongestive therapy consists of:

* Meticulous skin care with the use of emollients
* Using short stretch bandages or continuous wearing of a pressure garment
* Manual lymphatic drainage therapy
* Remedial exercises (e.g., aerobic exercise, strength training, and stretching exercises)

Study group (B) Cold Compression Therapy group

Group Type EXPERIMENTAL

Cold Compression therapy

Intervention Type DEVICE

The BioCryo Cold Compression System is a cold therapy pneumatic compression device that safely administers sequential, gradient pneumatic compression and CryoTherapy combined.

complete decongestive therapy

Intervention Type OTHER

Complete decongestive therapy consists of:

* Meticulous skin care with the use of emollients
* Using short stretch bandages or continuous wearing of a pressure garment
* Manual lymphatic drainage therapy
* Remedial exercises (e.g., aerobic exercise, strength training, and stretching exercises)

Group (C) Control group

Group Type ACTIVE_COMPARATOR

complete decongestive therapy

Intervention Type OTHER

Complete decongestive therapy consists of:

* Meticulous skin care with the use of emollients
* Using short stretch bandages or continuous wearing of a pressure garment
* Manual lymphatic drainage therapy
* Remedial exercises (e.g., aerobic exercise, strength training, and stretching exercises)

Interventions

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Multi-waved Locked System Laser

The M6 therapy laser is a robotized multi-target device designed to treat patients suffering pathologies affecting a wide area, and to perform automatic applications.

Intervention Type DEVICE

Cold Compression therapy

The BioCryo Cold Compression System is a cold therapy pneumatic compression device that safely administers sequential, gradient pneumatic compression and CryoTherapy combined.

Intervention Type DEVICE

complete decongestive therapy

Complete decongestive therapy consists of:

* Meticulous skin care with the use of emollients
* Using short stretch bandages or continuous wearing of a pressure garment
* Manual lymphatic drainage therapy
* Remedial exercises (e.g., aerobic exercise, strength training, and stretching exercises)

Intervention Type OTHER

Other Intervention Names

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M6 therapy BioCryo Cold Compression System

Eligibility Criteria

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Inclusion Criteria

* Female patients with unilateral BCRL.
* Age of patients above 18 years old
* Patient history of modified radical mastectomy, chemotherapy and/or radiotherapy.
* Patients undertaken have history or current hormonal treatment.
* Patients with moderate lymphoedema (20-40% increase in extremity volume)

Exclusion Criteria

* Patients who have severe co-morbid diseases.
* Presence of other cancers, cancer recurrence, lymphatic malformation, or vascular disease
* Patients who are having current chemotherapy and/or radiotherapy.
* Patients who have bilateral lymphedema, current metastases, elephantiasis, infection, lymphangiosis carcinomatosa, cellulitis, venous thrombosis, or congestive heart failure
* Patients with musculoskeletal disorders affecting upper extremity.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Sherine Omar Abdelaziz Mohamed Elsherif

assistant lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mohamed H El-Gendy, professor

Role: STUDY_CHAIR

Cairo University

Locations

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Kasr El-Einy Center of Radiation Oncology and Nuclear Medicine, Faculty of Medicine, Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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004539

Identifier Type: -

Identifier Source: org_study_id

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