Effect of Different Bandage Interface Pressures on Breast Cancer Related Lymphedema

NCT ID: NCT05660590

Last Updated: 2022-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

21 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-06-01

Study Completion Date

2022-05-18

Brief Summary

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The goal of this randomised comparison study is to compare different bandage interface pressures in individuals with breast cancer related lymphedema

The main questions it aims to answer are:

* Is high or low bandage pressure effective in reducing edema and soft tissue thickness?
* do bandages applied with high or low bandage pressure comprimise sleep, comfort or subjective benefit from treatment?

Participants will recieve complex decongestive physiotherapy. Bandage will apply high or low pressure. Effects of high and low bandage interface pressures will compare

Detailed Description

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The aim of this study was to evaluate the effect of compression bandage applied with different pressures on skin and subcutaneous thickness in individuals with breast cancer-related lymphedema.

individuals with stage 2 unilateral lymphedema participated in the study. Skin and subcutaneous thicknesses, extremity volumes, sleep quality, treatment benefit, comfort during treatment were evaluated respectively by ultrasound from 6 reference points as dorsum of hand, wrist volar, forearm dorsum, forearm volar, arm dorsum, arm volar, volumetric measurement, Pittsburgh Sleep Quality Index, Patient Benefit Index-Lymphedema, and visual analog scale. Complex decongestive physiotherapy was applied to individuals randomly divided into two groups: low (20-30 mmHg) and high bandage pressure (45-55 mmHg). Individuals were evaluated before treatment, at 1st, 10th session, end of treatment, and at 3 months follow-up.

Conditions

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Lymphedema of Upper Limb Breast Cancer Lymphedema Edema Arm

Keywords

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compelex decongestive physiotherapy bandage interface pressure compression therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomised comparison trial
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
radiologist who assessed soft tissue thickness assessment is masked and the patients did't know which group they belong to.

Study Groups

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Low bandage pressure

Compression bandages applied with low pressure (20-30 mmHg)

Group Type ACTIVE_COMPARATOR

complex decongestive physiotherapy with low pressure compression bandage

Intervention Type OTHER

both group received complex decongestive physiotherapy consist of manual lymph dranaige, skin care, exercise and compression bandage. Every component except compression bandage applied exacly the same to both group. Compression bandage applied with low bandage interface pressure (20-30 mmHg)

high bandage pressure

Compression bandages applied with low pressure (45-55 mmHg)

Group Type ACTIVE_COMPARATOR

complex decongestive physiotherapy with high pressure compression bandage

Intervention Type OTHER

complex decongestive physiotherapy consist of manual lymph dranaige, skin care, exercise and compression bandage. Every component except compression bandage applied exacly the same to both group. Compression bandage applied with high bandage interface pressure (45-55 mmHg)

Interventions

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complex decongestive physiotherapy with low pressure compression bandage

both group received complex decongestive physiotherapy consist of manual lymph dranaige, skin care, exercise and compression bandage. Every component except compression bandage applied exacly the same to both group. Compression bandage applied with low bandage interface pressure (20-30 mmHg)

Intervention Type OTHER

complex decongestive physiotherapy with high pressure compression bandage

complex decongestive physiotherapy consist of manual lymph dranaige, skin care, exercise and compression bandage. Every component except compression bandage applied exacly the same to both group. Compression bandage applied with high bandage interface pressure (45-55 mmHg)

Intervention Type OTHER

Other Intervention Names

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Low bandage interface pressure High bandage interface pressure

Eligibility Criteria

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Inclusion Criteria

* Stage 2 unilateral BCRL involving whole extremity according to ISL
* To be volunteer.

Exclusion Criteria

* Acute deep vein thrombosis
* Acute soft tissue infection
* Peripheral artery disease in upper extremity
* Systemic diseases with peripheral edema (kidney, hearth insufficiency etc.),
* Allergy to materials used for treatment
* Mental diseases effect cooperation
* Sensory loss in the effected limb
* Open wound in the effected limb.
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Abant Izzet Baysal University

OTHER

Sponsor Role lead

Responsible Party

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Elif Duygu

Research assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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elif duygu yıldız, Dr

Role: PRINCIPAL_INVESTIGATOR

Abant Izzet Baysal University

Locations

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Abany Izzet Baysal University

Bolu, Center, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Duygu-Yildiz E, Bakar Y, Hizal M. The effect of complex decongestive physiotherapy applied with different compression pressures on skin and subcutaneous tissue thickness in individuals with breast cancer-related lymphedema: a double-blinded randomized comparison trial. Support Care Cancer. 2023 Jun 7;31(7):383. doi: 10.1007/s00520-023-07843-y.

Reference Type DERIVED
PMID: 37285046 (View on PubMed)

Other Identifiers

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BAIBU-FTR-ED-001

Identifier Type: -

Identifier Source: org_study_id