Pre-Surgical Grading System of Asherman Syndrome

NCT ID: NCT05901948

Last Updated: 2023-06-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

65 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-07

Study Completion Date

2023-03-15

Brief Summary

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Utilising a novel pre-surgical grading system to class cases of asherman syndrome into 3 groups based on expected difficulty of surgery and potential prognostic outcomes.

Detailed Description

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Using the grading system, patients are classified into Mild, Moderate and Severe Asherman Syndrome. With the mild disease having the best prognostic value and a 1 step procedure, Moderate cases having a mediocre prognosis and usually multi-step procedure and Severe cases having a poor prognosis and counseled to other options. This observational study looks at the surgical outcomes following hysteroscopy for cases graded according to the new system to identify the accuracy of the classification in predicting the surgical success and prognostic value.

Conditions

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Asherman Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Asherman Patients

Patients diagnosed with Asherman syndrome based on patient complaint of hypomenorrhea or amenorrhea and hysterosalpingography.

Classification

Intervention Type OTHER

Novel Asherman Scoring Classification

Interventions

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Classification

Novel Asherman Scoring Classification

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Asherman Syndrome
* intra-uterine synechiae

Exclusion Criteria

* patients with a fundectomy or uterine reduction surgery.
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ebtesama Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yehia Shawki

Endoscopy unit director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Osama Shawki, MD

Role: STUDY_CHAIR

Cairo University

Locations

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Ebtesama Hospital

Cairo, , Egypt

Site Status

Countries

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Egypt

References

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Dreisler E, Kjer JJ. Asherman's syndrome: current perspectives on diagnosis and management. Int J Womens Health. 2019 Mar 20;11:191-198. doi: 10.2147/IJWH.S165474. eCollection 2019.

Reference Type RESULT
PMID: 30936754 (View on PubMed)

Salazar CA, Isaacson K, Morris S. A comprehensive review of Asherman's syndrome: causes, symptoms and treatment options. Curr Opin Obstet Gynecol. 2017 Aug;29(4):249-256. doi: 10.1097/GCO.0000000000000378.

Reference Type RESULT
PMID: 28582327 (View on PubMed)

Di Guardo F, Della Corte L, Vilos GA, Carugno J, Torok P, Giampaolino P, Manchanda R, Vitale SG. Evaluation and treatment of infertile women with Asherman syndrome: an updated review focusing on the role of hysteroscopy. Reprod Biomed Online. 2020 Jul;41(1):55-61. doi: 10.1016/j.rbmo.2020.03.021. Epub 2020 Apr 28.

Reference Type RESULT
PMID: 32444259 (View on PubMed)

Other Identifiers

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100032023002

Identifier Type: -

Identifier Source: org_study_id

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