Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area for Prediction of Post Spinal Hypotension

NCT ID: NCT04780139

Last Updated: 2021-07-23

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 62 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-03-01
• Study Completion Date: 2021-07-21

Brief Summary

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH.

Detailed Description

The aim of this study is to evaluate the efficacy of internal jugular cross sectional area for predicting the occurrence of PSAH. Spinal anaesthesia is frequently used in daily clinical practice. Postspinal anaesthesia hypotension (PSAH) is a common side effect with an incidence of 15.3 to 33% that may result in organ hypoperfusion and ischaemic events. Patients' susceptibility to intraoperative hypotension can be influenced by the sensory block level, age, preoperative volume status , physical status, pre-operative medications and fasting.

PSAH due to spinal blockade is principally a consequence of diminished systemic vascular resistance after blockade of preganglionic sympathetic fibres. Many attempts have been tried to prevent PSAH, such as intravenous volume preload or prophylactic vasopressors. However, fluid infusion has been proved to lower the incidence of PSAH and significantly decrease vasopressor requirements. At the same time, empirical volume loading carries the potential of volume overload, particularly in patients with cardiac disease. Consequently, the search for predictors of PSAH is becoming mandatory to avoid blind volume loading and reserve it only for patients who are expected to develop PSAH. .

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Conditions

Post-spinal Anesthesia Hypotension

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: PROSPECTIVE

Interventions

Ultrasonographic Evaluation of Internal Jugular Vein Cross Sectional Area

Measuring the internal jugular vein cross section area and relate this to the incidence of hypotension after spinal anesthesia.

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• patients more than 40 years of age.
• American Society of Anesthesiologists' (ASA) physical status 1 or 2.
• scheduled for elective surgery under spinal anaesthesia in the supine position.

Exclusion Criteria

• BMI more than 35 kg m2.
• taking angiotensin converting enzyme inhibitors.
• pregnant women.
• emergency cases.
• absolute or relative contraindications to spinal anaesthesia.
• Also, patients with a baseline arterial systolic blood pressure less than 90 mmHg or mean arterial blood pressure (MBP) less than 70 mmHg will be excluded.

• Minimum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Walid Nofal

Assisstant professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Sanaa Farag Mahmoud, MD

Role: PRINCIPAL_INVESTIGATOR

Anesthesiology Department, Faculty of Medicine, Ain Shams University

Eman Sabek, MD

Role: PRINCIPAL_INVESTIGATOR

Radiology department, National Centre of Radiation Research and Technology, Atomic Energy Authority

WALID Nofal, MD

Role: PRINCIPAL_INVESTIGATOR

Anesthesiology department, Faculty of Medicine, Ain Shams Unive

Locations

Ain Shams University hospital

Cairo, Cairo Governorate, Egypt

Countries

Egypt

Other Identifiers

FMASU R 25/2020/2021

Identifier Type: -

Identifier Source: org_study_id