Adenomyosis in Fertile Women in MUSA Criteria

NCT ID: NCT06250569

Last Updated: 2024-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

144 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-29

Study Completion Date

2025-07-31

Brief Summary

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1. To estimate the prevalence of adenomyosis in fertile women aged 18-30 years using the revised MUSA ultrasound criteria.
2. To evaluate clinical risk factors that are associated with adenomyosis diagnosis in this population

Detailed Description

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Adenomyosis is a benign condition characterized by the presence endometrial glands and stroma within the myometrium. Its prevalence varies from 5-70%. The definitive diagnosis of adenomyosis is based mainly on histological assessment of hysterectomy specimens. This led to a concept that adenomyosis affects only parous women between 35-50 years who complain of dysmenorrhea and heavy menstrual bleeding. Magnetic Resonance Imaging (MRI) can detect adenomyosis with a sensitivity of 80%. Transvaginal ultrasound using the revised Morphological Uterus Sonographic Assessment (MUSA) criteria can detect adenomyosis non-invasively at a lower cost. Such advancements in imaging techniques allow studying the prevalence of the disease in wider range of population including young women.

Conditions

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Adenomyosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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first group

women with with adenomyosis

No interventions assigned to this group

second group

women without adenomyosis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* women with regular menstrual cycle attending outpatient clinic for contraception counseling
* age 18 -30 years old

Exclusion Criteria

* Women on hormonal contraception
* Infertile women
* Associated pathologies like endometriosis, uterine fibroids. and ovarian cysts
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Aya nour Elzanaty

principal invistigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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safwat abdelrady, Prof

Role: STUDY_DIRECTOR

Assiut University

Locations

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Assuit university

Asyut, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Aya Nour elzanaty, MBBch

Role: CONTACT

01022739886

Essam Rashad, Prof

Role: CONTACT

01001330534

Facility Contacts

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Aya Nour Elzanaty

Role: primary

01022739886

References

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Marion LL, Meeks GR. Ectopic pregnancy: History, incidence, epidemiology, and risk factors. Clin Obstet Gynecol. 2012 Jun;55(2):376-86. doi: 10.1097/GRF.0b013e3182516d7b.

Reference Type BACKGROUND
PMID: 22510618 (View on PubMed)

Practice Committee of American Society for Reproductive Medicine. Medical treatment of ectopic pregnancy. Fertil Steril. 2008 Nov;90(5 Suppl):S206-12. doi: 10.1016/j.fertnstert.2008.08.049.

Reference Type BACKGROUND
PMID: 19007632 (View on PubMed)

Karol D, Williamson M, Pereira N. Successful Expectant Management of a Tubal Ectopic Pregnancy. J Minim Invasive Gynecol. 2024 Feb;31(2):92-94. doi: 10.1016/j.jmig.2023.11.011. Epub 2023 Nov 30. No abstract available.

Reference Type BACKGROUND
PMID: 38042476 (View on PubMed)

Harmsen MJ, Van den Bosch T, de Leeuw RA, Dueholm M, Exacoustos C, Valentin L, Hehenkamp WJK, Groenman F, De Bruyn C, Rasmussen C, Lazzeri L, Jokubkiene L, Jurkovic D, Naftalin J, Tellum T, Bourne T, Timmerman D, Huirne JAF. Consensus on revised definitions of Morphological Uterus Sonographic Assessment (MUSA) features of adenomyosis: results of modified Delphi procedure. Ultrasound Obstet Gynecol. 2022 Jul;60(1):118-131. doi: 10.1002/uog.24786.

Reference Type BACKGROUND
PMID: 34587658 (View on PubMed)

Other Identifiers

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Adenomyosis in fertile womens

Identifier Type: -

Identifier Source: org_study_id

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