Ultrasound Elastography in Diffferentiation of Endometriomas and Hemorrhagic Cysts

NCT ID: NCT05104086

Last Updated: 2021-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-12-25

Study Completion Date

2021-12-25

Brief Summary

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To investigate the value of ultrasound elastography in differentiating endometriomas from ovarian hemorrhagic cysts

Detailed Description

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The participants will be subjected to:

* Personal, Obstetric and gynecological History taking.
* Clinical examination.
* B-mode ultrasonography was performed to characterize the adnexal masses morphologically.
* Color Doppler ultrasound.
* Grayscale and elastographic ultrasound examination, which will be done using acoustic radiation force impulse (ARFI) imaging with virtual touch quantification (VTQ). Five consecutive measurements were recorded for each lesion from the region identified as the region of interest (ROI) and the median of these measurements was recorded as the shear wave velocity (SWV) value of the lesion. In virtual touch quantification (VTQ) the shear wave speed is expressed in m/s. Only numerical results will be taken into consideration.

. Realtime elastographic and B-mode images simultaneously will appear as a two-panel image. Elastogram appeared in the region of interest (ROI) box to determine the target ovarian lesion and surrounding tissue, then elasticity colour code will be classified in 5 patterns : pattern 1, an absent or a very small hard area; pattern 2, hard area 45 per cent; pattern 4, peripheral hard and central soft areas; pattern 5, hard area occupying entire solid component with or without soft rim. Strain index will be analyzed, which will be obtained by comparing the absolute strain value of solid component of ovarian cyst with that of surrounding soft tissue.
* The invistigator will reevaluate the lesions 4 weeks after the initial assessment to see the possible changes in the size and/or configuration of the lesions with B-mode and elastographic ultrasonography.
* Lesion will be evaluated as endometriomas and referred for surgery when shows no significant changes in size and configuration.
* Hemorrhagic cyst diagnosis will be made if the lesion had resolved on follow-up.

Conditions

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Ovarian Endometrioma

Keywords

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ultrasound elastography

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Parallel Assignment
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Investigators
Single investigator

Study Groups

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evaluate the value of ultrasound elastography in dignosis of endometriomas

evaluation of endometrioma by ultrasound elastography and will be repeated after 4 weeks

Group Type ACTIVE_COMPARATOR

ultrasound elastography

Intervention Type DEVICE

strain ratio and resistivity index

evaluate the value of ultrasound elastography in ovarian hemorrhagic cysts

revaluation of ovarian hemorrhagic cyst by ultrasound elastography and noticing the change of values

Group Type ACTIVE_COMPARATOR

ultrasound elastography

Intervention Type DEVICE

strain ratio and resistivity index

Interventions

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ultrasound elastography

strain ratio and resistivity index

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient suspected to have endometrioma or hemorrhagic ovarian cysts.

Exclusion Criteria

* Simple cysts which were defined as a sonolucent thin-walled (\<3 mm thick) cyst larger than 3 cm in diameter without septations or papillary projections \[12\].
* Hemorrhagic cysts containing septations or mural nodules with detectable flow on Doppler ultrasonography
Minimum Eligible Age

18 Years

Maximum Eligible Age

52 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Mansoura University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alaa mosbah, professor

Role: PRINCIPAL_INVESTIGATOR

Mansoura university faculty of medicine,obestetric and gynecology department

Locations

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Mansoura University

Al Mansurah, Dakahlia Governorate, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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hala hafez, resident

Role: CONTACT

Phone: 00201027292006

Email: [email protected]

alaa mosbah, professor

Role: CONTACT

Email: [email protected]

Facility Contacts

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hala hafez, resident

Role: primary

alaa mosbah, professor

Role: backup

Other Identifiers

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MS.19.09.821

Identifier Type: -

Identifier Source: org_study_id