Validation of Emergency Surgery Score (ESS) in Egyptian Patients Undergoing Emergency Laparotomy

NCT ID: NCT05639920

Last Updated: 2022-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

138 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-31

Study Completion Date

2024-02-29

Brief Summary

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To assess the accuracy of Emergency Surgery Score in predicting postoperative morbidity and mortality in emergency laparotomy.

Detailed Description

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Emergency laparotomy is the most common emergency surgery which considered a life saving exploratory procedure for which the clinical presentation, underlying pathology, anatomical site of surgery, and preoperative management vary considerably. There are more than 400 OPCS codes describing surgery that could come under the umbrella term of 'emergency laparotomy' which reflect the diverse nature of this surgical cohort. In spite the lack of data on the outcomes of emergency laparotomies it is generally considered very poor mortality rates following emergency laparotomy Internationally reported range from 13% to 18% at 30 days Even after innumerable advances in surgical skills, antimicrobial agents and supportive care. There is a need for early prognostic evaluation of these individuals to identify patients in high risk for more agressive treatment Using an ideal scoring system will help in ;.making appropriate decision on those patients. accurately predicting the risk of developing serious complications or die . Categorizing patients into different risk groups which would help to prognosticate the outcome, select patients for intensive care and determine operative risk, thereby helping to choose the nature of the operative procedure .

The Emergency Surgery Score (ESS) was developed as a novel preoperative risk assessment tool for patients undergoing EGS in 2016 ESS accurately predicts outcomes in all types of emergent laparotomy patients and may prove valuable as a bedside decision-making tool for patient and family counseling, as well as for adequate risk-adjustment in emergent laparotomy quality benchmarking efforts.10

Conditions

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Emergencies

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Group A

Scoreing

Intervention Type COMBINATION_PRODUCT

Validation of Emergency surgery score in predicting mortality and mortality in Egyptian patients undergoing Emergency laparotomy

Interventions

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Scoreing

Validation of Emergency surgery score in predicting mortality and mortality in Egyptian patients undergoing Emergency laparotomy

Intervention Type COMBINATION_PRODUCT

Eligibility Criteria

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Inclusion Criteria

* Patients more who are 18 years old or older.
* Patients who are in need of an emergency laparotomy within 24 hours of admission.

Exclusion Criteria

* Patients less than 18 years old.
* Patients who are not accessible for follow up to the 30th postoperative day.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Doaa Ahmed Mohamed

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Doaa A. Mohamed

Role: CONTACT

+201111834281

Jehan A. Sayed

Role: CONTACT

+20100 625 3939

References

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Nag DS. Assessing the risk: Scoring systems for outcome prediction in emergency laparotomies. Biomedicine (Taipei). 2015 Dec;5(4):20. doi: 10.7603/s40681-015-0020-y. Epub 2015 Nov 28.

Reference Type BACKGROUND
PMID: 26615537 (View on PubMed)

Saunders DI, Murray D, Pichel AC, Varley S, Peden CJ; UK Emergency Laparotomy Network. Variations in mortality after emergency laparotomy: the first report of the UK Emergency Laparotomy Network. Br J Anaesth. 2012 Sep;109(3):368-75. doi: 10.1093/bja/aes165. Epub 2012 Jun 22.

Reference Type BACKGROUND
PMID: 22728205 (View on PubMed)

Rix TE, Bates T. Pre-operative risk scores for the prediction of outcome in elderly people who require emergency surgery. World J Emerg Surg. 2007 Jun 5;2:16. doi: 10.1186/1749-7922-2-16.

Reference Type BACKGROUND
PMID: 17550623 (View on PubMed)

Ahuja A, Pal R. Prognostic scoring indicator in evaluation of clinical outcome in intestinal perforations. J Clin Diagn Res. 2013 Sep;7(9):1953-5. doi: 10.7860/JCDR/2013/6572.3375. Epub 2013 Sep 10.

Reference Type BACKGROUND
PMID: 24179907 (View on PubMed)

Mercer S, Guha A, Ramesh V. The P-POSSUM scoring systems for predicting the mortality of neurosurgical patients undergoing craniotomy: Further validation of usefulness and application across healthcare systems. Indian J Anaesth. 2013 Nov;57(6):587-91. doi: 10.4103/0019-5049.123332.

Reference Type BACKGROUND
PMID: 24403619 (View on PubMed)

Neary WD, Heather BP, Earnshaw JJ. The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM). Br J Surg. 2003 Feb;90(2):157-65. doi: 10.1002/bjs.4041.

Reference Type BACKGROUND
PMID: 12555290 (View on PubMed)

Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, Sirio CA, Murphy DJ, Lotring T, Damiano A, et al. The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest. 1991 Dec;100(6):1619-36. doi: 10.1378/chest.100.6.1619.

Reference Type BACKGROUND
PMID: 1959406 (View on PubMed)

Chang RW. Individual outcome prediction models for intensive care units. Lancet. 1989 Jul 15;2(8655):143-6. doi: 10.1016/s0140-6736(89)90193-1.

Reference Type BACKGROUND
PMID: 2567904 (View on PubMed)

Kongkaewpaisan N, Lee JM, Eid AI, Kongwibulwut M, Han K, King D, Saillant N, Mendoza AE, Velmahos G, Kaafarani HMA. Can the emergency surgery score (ESS) be used as a triage tool predicting the postoperative need for an ICU admission? Am J Surg. 2019 Jan;217(1):24-28. doi: 10.1016/j.amjsurg.2018.08.002. Epub 2018 Aug 23.

Reference Type BACKGROUND
PMID: 30172358 (View on PubMed)

Peponis T, Bohnen JD, Sangji NF, Nandan AR, Han K, Lee J, Yeh DD, de Moya MA, Velmahos GC, Chang DC, Kaafarani HMA. Does the emergency surgery score accurately predict outcomes in emergent laparotomies? Surgery. 2017 Aug;162(2):445-452. doi: 10.1016/j.surg.2017.03.016. Epub 2017 May 26.

Reference Type BACKGROUND
PMID: 28554491 (View on PubMed)

Vasileiou G, Ray-Zack M, Zielinski M, Qian S, Yeh DD, Crandall M. Validation of the American Association for the Surgery of Trauma emergency general surgery score for acute appendicitis-an EAST multicenter study. J Trauma Acute Care Surg. 2019 Jul;87(1):134-139. doi: 10.1097/TA.0000000000002319.

Reference Type BACKGROUND
PMID: 31259871 (View on PubMed)

Montasser M, Ellisy DAM, Sayed JA, Makkey MM. Validation of Emergency Surgery Score (ESS) as outcome prediction score in Egyptian patients undergoing emergency laparotomy. Int J Emerg Med. 2025 Jul 7;18(1):124. doi: 10.1186/s12245-025-00934-z.

Reference Type DERIVED
PMID: 40624475 (View on PubMed)

Other Identifiers

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Emergency surgery score

Identifier Type: -

Identifier Source: org_study_id

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