Recurrent Salivary Gland Infections in Covid-19

NCT ID: NCT05890547

Last Updated: 2023-06-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-06-01

Study Completion Date

2023-12-31

Brief Summary

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The aim of this study is to find out the role of Covid-19 in salivary gland infection and its recurrence.

Detailed Description

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This is a prospective clinical study of 60 patients. The study will be performed in the Otolaryngology department, Faculty of Medicine, Benha University during the duration from June 2023 to December 2023.

Inclusion criteria:

Adult patients aged ≥18 years.

Exclusion criteria:

* Patients with known autoimmune diseases,
* Diabetes Mellitus
* History of cancer in the region of the head and neck or previous radio and/or chemotherapy.
* History of facial nerve palsy,
* Oral and dental diseases including chronic sialadenitis or sialolithiasis.
* previous oral surgery.

Patients were divided into two equal groups each of 30 patients according to the cause of infection. Group (1) comprises 30 patients with Covid-19 infection representing the study group COVID-19 diagnosis will be based on a positive SARS-CoV-2 nasopharyngeal swab on real-time reverse transcription-polymerase chain reaction (RT-PCR) in the presence of clinical and/or radiological signs and group (2) comprises of 30 patients with non-Covid-19 infection as a control group.

All patients will be submitted to full ENT and intraoral clinical examination. We will Compare both groups as regards patients' characteristics, risk factors, etiology, symptoms, and rate of recurrence of sialadenitis.

Conditions

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Recurrent Salivary Gland Infections in Covid-19

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Study group

comprises 30 patients with Covid-19 infection representing the study group COVID-19 diagnosis will be based on a positive SARS-CoV-2 nasopharyngeal swab on real-time reverse transcription-polymerase chain reaction (RT-PCR) in the presence of clinical and/or radiological signs.

No interventions assigned to this group

Control group

comprises 30 patients without a history of Covid-19 infection as a control group.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adult patients aged ≥18 years with a history of CIVID-19 infection in the study group and of similar age without a history of COVID-19 infection.

Exclusion Criteria

* Patients with known autoimmune diseases,
* Diabetes Mellitus
* History of cancer in the region of the head and neck or previous radio and/or chemotherapy.
* History of facial nerve palsy,
* Oral and dental diseases including chronic sialadenitis or sialolithiasis.
* previous oral surgery.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Eslam Farid Abu Shady ,MD

lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eslam Abu Shady, MD

Role: PRINCIPAL_INVESTIGATOR

medical school

Locations

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Benha university hospitals

Banhā, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Benha university

Identifier Type: OTHER

Identifier Source: secondary_id

RC 21-4-2023

Identifier Type: -

Identifier Source: org_study_id

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