Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl

NCT ID: NCT05875506

Last Updated: 2025-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-01

Study Completion Date

2023-09-01

Brief Summary

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Efficacy of ozone gel, doxycycline saturated chitosan dressing versus Alveogyl in pain alleviation and healing of alveolar osteitis in diabetic patients

Detailed Description

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Conditions

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Osteitis Dry Socket

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Ozone gel

(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728)

Group Type EXPERIMENTAL

Ozone gel

Intervention Type DRUG

(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728) applied in dry socket

doxycycline hyclate saturated chitosan dressing

doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA)

Group Type EXPERIMENTAL

doxycycline hyclate saturated chitosan dressing

Intervention Type DRUG

doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA) applied in dry socket

Alveogyl paste

Alveogyl paste ( Septodont, inc, france)

Group Type ACTIVE_COMPARATOR

Ozone gel

Intervention Type DRUG

(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728) applied in dry socket

doxycycline hyclate saturated chitosan dressing

Intervention Type DRUG

doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA) applied in dry socket

Interventions

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Ozone gel

(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728) applied in dry socket

Intervention Type DRUG

doxycycline hyclate saturated chitosan dressing

doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA) applied in dry socket

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients over 20 years and under 60 years of age
* DM controlled by medication, presented to outpatient clinic with signs and symptoms of dry socket
* Only participant that are willing to control and record blood glucose level throughout the study period

Exclusion Criteria

* Patients with any significant medical condition (besides DM)
* Alcoholic individuals
* Patients on drugs that affect the central nervous systems
* Patients who reported the use of drugs that might interfere with pain sensitivity
* Pregnant and lactating women
* Hypersensitivity to local anesthetics
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Tarek Abdelbarry

Lecturer of Oral and Maxillofacial Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Dentistry, Minia University

Minya, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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713

Identifier Type: -

Identifier Source: org_study_id

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