Acute Effects of Exercise at Different Temperatures in Allergic Rhinitis Patient

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-01

Study Completion Date

2023-01-23

Brief Summary

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The purpose of this study was to determine the effects of exercise at different temperatures on nasal blood flow and symptoms in allergic rhinitis patients.

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Detailed Description

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Fifteen patients with allergic rhinitis aged between 18 and 35 years who had a positive skin prick test to house dust mite (D. pteronyssinus). The experiment was a crossover design in which each participant was given aerobic exercise by ergometer in two difference temperatures room : 25 degree celsius and 34 degree celsius. Rhinitis symptoms, nasal blood flow, heart rate, and oxygen saturation were measured before, during exercise at 15, 30, and 45 minutes, and after exercise at 0, 15 and 30 minutes in each temperature. Moreover, blood pressure, peak nasal inspiratory flow, pulmonary functions, respiratory muscle strength, and fractional exhaled nitric oxide were measured before and after exercise at 0, 15 and 30 minutes in each temperature.

Conditions

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Allergic Rhinitis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Fifteen patients with allergic rhinitis aged between 18 and 35 years who had a positive skin prick test to house dust mite (D. pteronyssinus). The experiment was a crossover design in which each participant was given aerobic exercise by ergometer in two difference temperatures room : 25 degree celsius and 34 degree celsius. Rhinitis symptoms, nasal blood flow, heart rate, and oxygen saturation were measured before, during exercise at 15, 30, and 45 minutes, and after exercise at 0, 15 and 30 minutes in each temperature. Moreover, blood pressure, peak nasal inspiratory flow, pulmonary functions, respiratory muscle strength, and fractional exhaled nitric oxide were measured before and after exercise at 0, 15 and 30 minutes in each temperature.

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Exercise in room temperature at 25 degree Celsius.

The participants received a moderate exercise program of cycling at moderate intensity (50-60% HRR) for 60 minutes in room temperature at 25 degree Celsius.

Group Type EXPERIMENTAL

Cycling exercise in room temperature at 25 degree Celsius.

Intervention Type OTHER

The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 25 degree Celsius.

Exercise in room temperature at 34 degree Celsius.

The participants received a moderate exercise program of cycling at moderate intensity (50-60% HRR) for 60 minutes in room temperature at 34 degree Celsius.

Group Type EXPERIMENTAL

Cycling exercise in room temperature at 34 degree Celsius.

Intervention Type OTHER

The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 34 degree Celsius.

Interventions

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Cycling exercise in room temperature at 25 degree Celsius.

The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 25 degree Celsius.

Intervention Type OTHER

Cycling exercise in room temperature at 34 degree Celsius.

The participants received a aerobic exercise of cycling for 60 minutes in room temperature at 34 degree Celsius.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subjects had a clinical history of persistent rhinitis, and had positive skin prick test to house dust mite (D. pteronyssinus)
* Persistent allergic rhinitis
* Subjects with known asthma, chronic rhinosinusitis, Lung cancer and Emphysema diseases were excluded.
* BMI 18.5 - 24.9 kg/m2
* Subjects will ask to abstain from taking antihistamine for at least 5 days, leukotriene receptor antagonist for at least 1 week, and nasal steroids for at least 2 weeks prior to the start of the experiment.
* Subjects will ask to abstain from taking any form of dietary supplement during the experiment.
* Subjects had no exercise training program (not exercise regularly or not exercise for 30 minutes or more at least 3 times per week during the past 6 months)