Association Between Carotid Plaque Length and Cardiovascular Outcomes

NCT ID: NCT05843487

Last Updated: 2023-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-01-01

Study Completion Date

2030-12-31

Brief Summary

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This multicenter study involved 5 hospitals (Changhai Hospital; Yueyang Hospital of Shanghai University of Traditional Chinese Medicine; Gongli Hospital; Putuo Hospital of Shanghai University of Traditional Chinese Medicine; No. 904 Hospital of the PLA Joint Logistics Support Force Wuxi). The study enrolled 5000 consecutive patients without known CAD who underwent first coronary angiography for stable chest pain and carotid ultrasound was performed during hospitalization from January 2017 through December 2018.

Detailed Description

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Patients who had obstructive CAD (defined as ≥50% luminal stenosis) confirmed by coronary angiography and who underwent carotid scanning were included in the final analysis.Carotid ultrasonography was performed simultaneously, and carotid intima-media thickness (IMT), maximum thickness and length of all plaques were measured.The incidence of major adverse cardiovascular events was recorded during follow-up.

Conditions

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Coronary Artery Disease Carotid Plaque

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Carotid plaque length

Patients underwent carotid ultrasonography and first coronary angiography simultaneously

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent coronary angiography for stable chest pain and carotid ultrasound simultaneously;
* Patients with obstructive CAD (≥50% coronary stenosis);

Exclusion Criteria

* \<18 years of age;
* previous carotid surgery or significant carotid artery disease;
* prior stroke or transient ischemic attack;
* previously documented CAD (including history of myocardial infarction, acute coronary syndrome, or coronary revascularization);
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Yueyang Hospital, Shanghai University of Traditional Chinese medicine

UNKNOWN

Sponsor Role collaborator

Putuo Hospital, Shanghai University of Traditional Chinese Medicine

UNKNOWN

Sponsor Role collaborator

904th Hospital of the Joint Logistics Support Force of the PLA

OTHER

Sponsor Role collaborator

Gongli Hospital

UNKNOWN

Sponsor Role collaborator

Changhai Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pan Li, PhD

Role: PRINCIPAL_INVESTIGATOR

Changhai Hospital

Jian Jian Na, MD

Role: STUDY_DIRECTOR

Putuo Hospital

Liang Chen, MD

Role: STUDY_DIRECTOR

904th Hospital of the Joint Logistics Support Force of the PLA

Wei Zhang, MD

Role: STUDY_DIRECTOR

Gongli Hospital

Yawei Yang, MD

Role: STUDY_DIRECTOR

Yueyang Hospital

Locations

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No. 904 Hospital of the PLA Joint Logistics Support Force

Wuxi, Jiangsu, China

Site Status

Changhai Hospital

Shanghai, Shanghai Municipality, China

Site Status

Gongli Hospital

Shanghai, Shanghai Municipality, China

Site Status

Putuo Hospital

Shanghai, Shanghai Municipality, China

Site Status

Yueyang Hospital

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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CPL

Identifier Type: -

Identifier Source: org_study_id

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