Mechanisms of LV Remodeling in Hypertensive Patients Working on a Rotational Expeditionary Basis in the Arctic

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

550 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-10-16

Study Completion Date

2026-10-30

Brief Summary

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The main goal of our investigation is to study the mechanisms of formation of left ventricular remodeling in patients with hypertension, working on a rotational expedition basis in the Arctic.

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Detailed Description

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Hypothesis: In patients with hypertension working in the conditions of the Arctic shift, the combination of climatic and geographical factors and rotational expeditionary method of labor contributes to the increase in the left ventricular remodeling processes and leads to the formation of heart failure with preserved ejection fraction.

Conditions

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Heart Failure With Preserved Ejection Fraction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with hypertension of stages 1 and 2

Individuals with stage 1 and 2 hypertension living in a temperate climate zone and doing rotational shiftwork in the Arctic.

No interventions assigned to this group

Healthy volunteers

Virtually healthy individuals living in a temperate climate zone and and doing rotational shiftwork in the Arctic.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* The patient signed the informed consent

Exclusion Criteria

* Valvular pathology of the heart
* Past cardiac or cerebral complications
* Identified heart rhythm disturbances
* Coronary heart disease
* Patients with severe somatic pathology, whose prognostic survival rate does not exceed 1 year
* The presence of a mental disorder of organic origin

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes