Bolus Pouch Feed Study

NCT ID: NCT05822557

Last Updated: 2025-02-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-01

Study Completion Date

2024-01-25

Brief Summary

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The primary aim of this study is to evaluate the impact of introducing a new enteral tube feed on health and feeding related quality of life. Secondary aims are to assess ease of use, liking, compliance, gastrointestinal tolerance, nutrient intake, anthropometric changes and safety.

Detailed Description

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Bolus enteral tube feeding (termed 'bolus feeding') is an increasingly common method of providing nutritional support to home enterally tube fed (HETF) patients, particularly those who are more active and/or require greater flexibility in their feeding regimen. However, current methods of bolus feeding are complex to administer, messy, may be unhygienic, and require and lead to a significant amount of plastic waste. Therefore, there is a clear need for a simpler and optimised way to provide bolus feeds. The aim of this study is to evaluate the impact of introducing a new enteral tube feed on health and feeding related quality of life, ease of use, liking, compliance, gastrointestinal tolerance, nutritional intake, anthropometry and safety. This is a prospective, longitudinal, 28-day intervention study with a 7-day baseline period.

Conditions

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Cancer Neurological Disorder Gastrointestinal Dysfunction Oral Complication Stroke

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

This is a prospective, longitudinal, 28-day intervention study with a 7-day baseline period.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Bolus Pouch Feed

A 250 ml feeding pouch containing 400 kcal.

Group Type EXPERIMENTAL

Bolus Pouch Feed

Intervention Type OTHER

Following the 7-day baseline period, all patients will enter the 28-day intervention period, where they will receive the intervention feed daily. The feed prescription will be determined on an individual basis by the Dietitian responsible for the patient's nutritional management

Interventions

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Bolus Pouch Feed

Following the 7-day baseline period, all patients will enter the 28-day intervention period, where they will receive the intervention feed daily. The feed prescription will be determined on an individual basis by the Dietitian responsible for the patient's nutritional management

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ≥16 years of age
* Using or requiring an enteral tube feed as part of nutritional management plan
* Using or about to use bolus tube feeding methods at least once daily
* Expected to receive at least 400 kcal/day from the intervention feed
* Written or electronic informed consent from patient, or verbally given consent countersigned by a witness for those physically unable to sign.

Exclusion Criteria

* Parenteral nutrition contributing more than 70% of total energy requirements
* Patients with major hepatic dysfunction (i.e., decompensated liver disease)
* Patients with major renal dysfunction \[i.e., requiring filtration or stage 4/5 chronic kidney disease (CKD)\]
* Patients receiving inpatient care
* Participation in other clinical intervention studies within 2 weeks of this study
* Adults lacking mental capacity to consent
* Allergy to any study product ingredients
* Investigator concern regarding ability or willingness of patient to comply with the study requirements.
Minimum Eligible Age

16 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nutricia UK Ltd

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rebecca Stratton, PhD

Role: STUDY_CHAIR

Nutricia UK Ltd

Locations

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University Hospitals Sussex NHS Foundation Trust

Brighton, , United Kingdom

Site Status

Cambridge University Hospitals NHS Foundation Trust

Cambridge, , United Kingdom

Site Status

University Hospitals Coventry and Warwickshire NHS Trust

Coventry, , United Kingdom

Site Status

County Durham and Darlington NHS Foundation Trust

Darlington, , United Kingdom

Site Status

NHS Tayside

Dundee, , United Kingdom

Site Status

Royal Surrey NHS Foundation Trust

Guildford, , United Kingdom

Site Status

Betsi Cadwaladr University Health Board

Holywell, , United Kingdom

Site Status

Calderdale & Huddersfield NHS Foundation Trust

Huddersfield, , United Kingdom

Site Status

Leicestershire Partnership NHS Trust

Leicester, , United Kingdom

Site Status

North East London NHS Foundation Trust

London, , United Kingdom

Site Status

Northumbria Healthcare NHS Foundation Trust

Newcastle upon Tyne, , United Kingdom

Site Status

Nottingham University Hospitals NHS Trust

Nottingham, , United Kingdom

Site Status

Sheffield Teaching Hospitals NHS Foundation Trust

Sheffield, , United Kingdom

Site Status

Southern Health NHS Foundation Trust

Southampton, , United Kingdom

Site Status

South Warwickshire NHS Foundation Trust

Warwick, , United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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BOPFS2020

Identifier Type: -

Identifier Source: org_study_id

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