Weight Loss and Gastrostomy Tube Care Outcomes in Head and Neck Cancer Patients With Gastrostomy Tube Placement

NCT ID: NCT02775721

Last Updated: 2018-04-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-31

Study Completion Date

2018-12-31

Brief Summary

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Poor nutritional status and malnutrition are prevalent for patients undergoing treatment for head and neck cancer. Inadequate dietary intake is multi factorial, with patients experiencing dysphagia and or anorexia caused by various cancer treatments. Current standard practice utilizes Gastrostomy Tube placement to manage adverse nutritional effects related to Head and Neck cancer treatment.

Detailed Description

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The purpose of this study is to assess the quality of life and educational intervention outcomes of Head and Neck Cancer patients who have a gastrostomy tube placed per standard of care.

A high incident of Gastrostomy tube replacement occurs related to clogged, dislodged, and/or pulled out tubes. In addition, patients not eating or drinking after Gastrostomy tube placement, compounded by complications related to radiation treatment, results in decreased swallowing function. Inadequate swallow function, especially when combined with inadequate use of Gastrostomy tube, due to non-functional tube or insufficient patient knowledge in use of tube, results in poor nutritional status and excessive weight loss.

Conditions

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Malnutrition Gastrostomy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Cohort A

Head and Neck Cancer patients receiving Radiation Therapy Only. The purpose is to do a comparative analysis and identify if patient quality of life outcomes are the same, better or worse when compared to Cohorts B and C.

Interventions: The research nurse will provide gastrostomy tube care education and skin care education at each study visit utilizing the nursing process.

Speech therapy education and evaluation is assessed per standard of care by the attending speech therapist.

Nutritional therapy education and evaluation is assessed per the attending dietitian.

The European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H\&N35) and EORTC Core Questionnaire (QLQ-C30) version 3.0 will be completed by the subject.

Group Type OTHER

Nursing Education related to Gastrostomy Tube Care

Intervention Type OTHER

The research nurse will provide educational intervention at each study visit utilizing the nursing process.

Speech Therapy Education and Evaluation

Intervention Type OTHER

Speech therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Speech therapy and evaluation is assessed per the attending speech therapist. The study team will collect all data related to speech therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Nutritional Therapy Education and Evaluation

Intervention Type OTHER

Nutritional therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Nutritional therapy and evaluation is assessed per the attending dietitian. The study team will collect all data related to nutritional therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Quality of Life Questionnaire C30 version 3

Intervention Type OTHER

30-item instrument that measures the Health Related Quality of Life (HRQoL) in a wide range of cancer patient populations.

Quality of Life Questionnaire EORTC QLO - H&N35

Intervention Type OTHER

35-item instrument that measures the Health Related Quality of Life specific to Head and Neck cancer patient populations.

Cohort B

Head and Neck Cancer patients receiving Chemotherapy Only. The purpose is to do a comparative analysis and identify if patient quality of life outcomes are the same, better or worse when compared to Cohorts A and C.

Interventions: The research nurse will provide gastrostomy tube care education and skin care education at each study visit utilizing the nursing process.

Speech therapy education and evaluation is assessed per standard of care by the attending speech therapist.

Nutritional therapy education and evaluation is assessed per the attending dietitian.

The European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H\&N35) and EORTC Core Questionnaire (QLQ-C30) version 3.0 will be completed by the subject.

Group Type OTHER

Nursing Education related to Gastrostomy Tube Care

Intervention Type OTHER

The research nurse will provide educational intervention at each study visit utilizing the nursing process.

Speech Therapy Education and Evaluation

Intervention Type OTHER

Speech therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Speech therapy and evaluation is assessed per the attending speech therapist. The study team will collect all data related to speech therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Nutritional Therapy Education and Evaluation

Intervention Type OTHER

Nutritional therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Nutritional therapy and evaluation is assessed per the attending dietitian. The study team will collect all data related to nutritional therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Quality of Life Questionnaire C30 version 3

Intervention Type OTHER

30-item instrument that measures the Health Related Quality of Life (HRQoL) in a wide range of cancer patient populations.

Quality of Life Questionnaire EORTC QLO - H&N35

Intervention Type OTHER

35-item instrument that measures the Health Related Quality of Life specific to Head and Neck cancer patient populations.

Cohort C

Head and Neck Cancer patients receiving Chemotherapy and Radiation therapy. The purpose is to do a comparative analysis and identify if patient quality of life outcomes are the same, better or worse when compared to Cohorts A and B.

Interventions: The research nurse will provide gastrostomy tube care education and skin care education at each study visit utilizing the nursing process.

Speech therapy education and evaluation is assessed per standard of care by the attending speech therapist.

Nutritional therapy education and evaluation is assessed per the attending dietitian.

The European Organization for Research and Treatment of Cancer (EORTC) head and neck cancer module (QLQ-H\&N35) and EORTC Core Questionnaire (QLQ-C30) version 3.0 will be completed by the subject.

Group Type OTHER

Nursing Education related to Gastrostomy Tube Care

Intervention Type OTHER

The research nurse will provide educational intervention at each study visit utilizing the nursing process.

Speech Therapy Education and Evaluation

Intervention Type OTHER

Speech therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Speech therapy and evaluation is assessed per the attending speech therapist. The study team will collect all data related to speech therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Nutritional Therapy Education and Evaluation

Intervention Type OTHER

Nutritional therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Nutritional therapy and evaluation is assessed per the attending dietitian. The study team will collect all data related to nutritional therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Quality of Life Questionnaire C30 version 3

Intervention Type OTHER

30-item instrument that measures the Health Related Quality of Life (HRQoL) in a wide range of cancer patient populations.

Quality of Life Questionnaire EORTC QLO - H&N35

Intervention Type OTHER

35-item instrument that measures the Health Related Quality of Life specific to Head and Neck cancer patient populations.

Interventions

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Nursing Education related to Gastrostomy Tube Care

The research nurse will provide educational intervention at each study visit utilizing the nursing process.

Intervention Type OTHER

Speech Therapy Education and Evaluation

Speech therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Speech therapy and evaluation is assessed per the attending speech therapist. The study team will collect all data related to speech therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Intervention Type OTHER

Nutritional Therapy Education and Evaluation

Nutritional therapy will be conducted per standard of care, the protocol does not dictate the frequency or treatment plan of care. Nutritional therapy and evaluation is assessed per the attending dietitian. The study team will collect all data related to nutritional therapy education and evaluation at each study visit per protocol. All collected data will be utilized in final protocol analysis.

Intervention Type OTHER

Quality of Life Questionnaire C30 version 3

30-item instrument that measures the Health Related Quality of Life (HRQoL) in a wide range of cancer patient populations.

Intervention Type OTHER

Quality of Life Questionnaire EORTC QLO - H&N35

35-item instrument that measures the Health Related Quality of Life specific to Head and Neck cancer patient populations.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18 years and older
* Head and Neck cancer diagnosis
* Esophageal cancer diagnosis
* Receiving chemotherapy and/or radiation therapy
* Gastrostomy Tube placed within the last 30days or scheduled to have a gastrostomy tube placed within the next 30 days

Exclusion Criteria

* Not eligible for chemotherapy and/or radiation therapy
* Unwilling or unable to sign informed consent
* Any cognitive or mental deficits that would prevent patient from completing questionnaires or understanding educational interventions
* Current pre-existing Gastrostomy tube complications if a current Gastrostomy tube is in place prior to informed consent (i.e., skin breakdown, tube breakdown, other tube complications).
* No Gastrostomy tube placement
* Non-English Speaking
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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St. John Health System, Oklahoma

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Candida Barlow, MSN RN

Role: PRINCIPAL_INVESTIGATOR

St. John Health System

Locations

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St. John Health System

Tulsa, Oklahoma, United States

Site Status

Countries

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United States

Other Identifiers

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G-Tube

Identifier Type: -

Identifier Source: org_study_id

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