Operant Conditioning of Reflex Pathways to Improve Walking in Individuals Post-stroke

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

5 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-01

Study Completion Date

2025-12-31

Brief Summary

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The purpose of this study is to examine the changes in reflex pathways in the paretic ankle plantarflexors in individuals with post-stroke hemiparesis using operant conditioning. We are recruiting 5 individuals with chronic post-stroke hemiparesis with foot drop in the affected leg to participate in the reflex training procedure. The study involves 40 visits with a total study duration of about 4 months.

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Detailed Description

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Conditions

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Stroke Post-stroke Hemiparesis Foot Drop

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Reciprocal inhibition up conditioning

Each participant completes 6 baseline sessions and 30 up conditioning sessions. In the 30 conditioning sessions, the magnitude of reciprocal inhibition in the paretic leg of participants post-stroke will be up conditioned.

Group Type EXPERIMENTAL

Operant conditioning

Intervention Type BEHAVIORAL

In this training, individuals with post-stroke hemiparesis are trained to increase the amount of reciprocal inhibition in their paretic leg. By increasing the amount of reciprocal inhibition, the paretic ankle in people post-stroke may exhibit less foot drop.

Interventions

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Operant conditioning

In this training, individuals with post-stroke hemiparesis are trained to increase the amount of reciprocal inhibition in their paretic leg. By increasing the amount of reciprocal inhibition, the paretic ankle in people post-stroke may exhibit less foot drop.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* At least 6 months following a single, unilateral stroke, resulting in hemiparesis.
* Ambulatory with or without assistive device, but must demonstrate a gait deficit which is indicative of foot drop from reduced activation of the tibialis anterior muscle.
* Able to follow verbal directions.
* Able to see icons on computer monitor (with or without corrective lenses) from at least 4 feet away.
* All subjects will be adults at least 18 years old.
* Know history and current medication management for lower limb spasticity, if any.

Exclusion Criteria

* No history of ear disease or balance problems outside of those caused by the stroke.
* Cerebellar stroke
* No other neurological disease or injuries other than the stroke affecting the use of the legs and/or walking.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes