Promoting Safety Plan and Coping Strategy Use Among Adults With Suicidal Thoughts

NCT ID: NCT05791643

Last Updated: 2025-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

103 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-05

Study Completion Date

2024-09-03

Brief Summary

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The goal of this study is to learn about a new, real-time, smartphone-based intervention aimed to decrease risk for suicide in adults who have been hospitalized for suicidal thoughts or behaviors. The main questions the investigators aim to answer are:

* Is a real-time, smartphone-based intervention that promotes the use of safety plans and other coping strategies for suicidal thoughts feasible and acceptable?
* Does the real-time intervention result in increased use of safety plans and other coping strategies, and reduce suicidal thoughts?

Participants will:

* Answer questions about current suicidal thoughts on their smartphone up to 6 times each day while they are in the hospital and during the 4 weeks after they leave the hospital
* When they report elevated suicidal thoughts on a smartphone survey, be randomly assigned to receive or not receive automated, interactive reminders to use content from their personalized safety plan or general coping strategies
* Answer brief follow-up questions on their smartphone within a couple hours of receiving or not receiving automated reminders
* Give feedback on their experience with the real-time intervention

Detailed Description

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Effective, scalable interventions for the highest-risk time for suicide - after inpatient psychiatric hospitalization - are urgently needed. The safety planning intervention (Stanley \& Brown, 2012) involves developing a personalized list of prioritized coping strategies for suicidal crises, and has been shown to prevent suicidal behavior (e.g., Nuij et al., 2021). However, roughly 40% of patients with a safety plan never use it (Stanley et al., 2016). The safety plan also includes multiple components (e.g., different internal coping strategies, seeking social support), yet little is known about the internal and external contexts that may impact the accessibility and effectiveness of individual safety plan components. Improving both the ability to promote safety plan use when needed and the understanding of when specific coping strategies are most accessible and effective has the potential to optimize this already evidence-based intervention.

The aim of this study is to leverage the recent micro-randomized trial (MRT) design (Klasnja et al., 2015) to evaluate the proximal effects of automated, interactive, smartphone-based reminders to implement the safety plan and its coping strategies at different levels of suicidal urges and intent. Twenty-five (N = 25) adults hospitalized for suicidal thoughts or behaviors will undergo an intensive longitudinal monitoring protocol, which includes completing up to six brief smartphone surveys per day that assess momentary suicidal urges and intent on a 0 to 10 scale during hospitalization and the 28 days after discharge. After each post-discharge survey with reported high intensity suicidal urges or moderate intent, participants will be "micro-randomized" to receive either a series of automated interactive intervention messages or no intervention. Whether the message content is personalized (from the individual's safety plan) or general (top-rated from others' safety plans) and the specific coping strategy type(s) recommended will also be randomized. Brief proximal follow-up surveys will assess coping strategy use since the last survey prompting micro-randomization, perceived helpfulness of any coping strategies used, and momentary suicidal urges and intent. Qualitative and quantitative data on acceptability and feasibility will be collected from participants and used to inform future real-time intervention refinements. Preliminary efficacy data will be used to inform the development of future, larger-scale studies and the ultimate development of policies for novel just-in-time adaptive interventions that deliver the right time of support, at the right time, and in the right context, for individuals at risk for suicide.

Conditions

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Suicide

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

During the four weeks after hospital discharge, each time a participant reports elevated (\> 0 but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urge on a momentary smartphone survey, they will be randomized to either receive a real-time intervention or no real-time intervention promoting safety plan or coping strategy use. If randomized to receive a real-time intervention, the intervention type will also be randomized to consist of either recommended coping strategies from their personalized safety plan or general coping strategies for suicidal thoughts.

During the post-discharge phase, participants will have 24/7 access to their full safety plan within the study app. At reported high (\>= 8 out of 10) levels of suicidal intent, no micro-randomization will occur, and a longstanding risk management protocol that includes direct, phone-based outreach to participants for further risk assessment and intervention will be used.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Real-time intervention for promoting safety plan and coping strategy use

Momentary surveys in which elevated (non-zero but \< 8 out of 10) levels of suicidal intent or high (\>= 8 out of 10) suicidal urges are reported will be randomized either to receive a real-time intervention that consists of automated, interactive reminders with suggested strategies for coping with suicidal thoughts or no intervention.

If randomized to receive an intervention, the intervention type will also be randomized (at equal probabilities) to suggest either coping strategies from the participant's personalized safety plan or general common coping strategies.

Group Type EXPERIMENTAL

Personalized internal and external coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of the internal coping strategies and external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.

Personalized internal coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of the internal coping strategies from the participant's personalized safety plan.

Personalized external coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of the external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.

General internal and external coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) common internal and external coping strategies for suicidal thoughts.

General internal coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) common internal coping strategies for suicidal thoughts.

General external coping strategies

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) external coping strategies (i.e., sources of social support/distraction) for suicidal thoughts.

General internal coping strategies, relaxation

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, relaxation-based) coping strategies for suicidal thoughts.

General internal coping strategies, distraction

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, distraction-based) coping strategies for suicidal thoughts.

General internal coping strategies, physical activity

Intervention Type BEHAVIORAL

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, physical activity-based) coping strategies for suicidal thoughts.

Interventions

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Personalized internal and external coping strategies

A series of interactive, automated messages will recommend use of the internal coping strategies and external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.

Intervention Type BEHAVIORAL

Personalized internal coping strategies

A series of interactive, automated messages will recommend use of the internal coping strategies from the participant's personalized safety plan.

Intervention Type BEHAVIORAL

Personalized external coping strategies

A series of interactive, automated messages will recommend use of the external coping strategies (i.e., sources of social support/distraction) from the participant's personalized safety plan.

Intervention Type BEHAVIORAL

General internal and external coping strategies

A series of interactive, automated messages will recommend use of general (non-personalized) common internal and external coping strategies for suicidal thoughts.

Intervention Type BEHAVIORAL

General internal coping strategies

A series of interactive, automated messages will recommend use of general (non-personalized) common internal coping strategies for suicidal thoughts.

Intervention Type BEHAVIORAL

General external coping strategies

A series of interactive, automated messages will recommend use of general (non-personalized) external coping strategies (i.e., sources of social support/distraction) for suicidal thoughts.

Intervention Type BEHAVIORAL

General internal coping strategies, relaxation

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, relaxation-based) coping strategies for suicidal thoughts.

Intervention Type BEHAVIORAL

General internal coping strategies, distraction

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, distraction-based) coping strategies for suicidal thoughts.

Intervention Type BEHAVIORAL

General internal coping strategies, physical activity

A series of interactive, automated messages will recommend use of general (non-personalized) common internal (and specifically, physical activity-based) coping strategies for suicidal thoughts.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Experiencing suicidal thoughts as part of their inpatient admission
* Ownership of and access to a smartphone (while on the unit and following discharge)
* Ability to speak and write English fluently

Exclusion Criteria

* Any factor that impairs the ability to effectively participate in the study (e.g., significant cognitive impairment, intellectual disability, presence of violent behavior, psychotic illness/symptoms determined by the treating clinician to impair ability to understand the study or provide informed consent)
* Failure to correctly answer all true/false questions in the consent form
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Rebecca G. Fortgang, Ph.D.

Assistant Professor, Department of Psychiatry, Harvard Medical School

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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McLean Hospital

Belmont, Massachusetts, United States

Site Status

Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status

Countries

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United States

References

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Stanley B, Brown GK. Safety planning intervention: A brief intervention to mitigate suicide risk. Cognitive and Behavioral Practice. 2012; 19(2): 256-264. doi:10.1016/j.cbpra.2011.01.001

Reference Type BACKGROUND

Nuij C, van Ballegooijen W, de Beurs D, Juniar D, Erlangsen A, Portzky G, O'Connor RC, Smit JH, Kerkhof A, Riper H. Safety planning-type interventions for suicide prevention: meta-analysis. Br J Psychiatry. 2021 Aug;219(2):419-426. doi: 10.1192/bjp.2021.50.

Reference Type BACKGROUND
PMID: 35048835 (View on PubMed)

Stanley B, Chaudhury SR, Chesin M, Pontoski K, Bush AM, Knox KL, Brown GK. An Emergency Department Intervention and Follow-Up to Reduce Suicide Risk in the VA: Acceptability and Effectiveness. Psychiatr Serv. 2016 Jun 1;67(6):680-3. doi: 10.1176/appi.ps.201500082. Epub 2016 Feb 1.

Reference Type BACKGROUND
PMID: 26828397 (View on PubMed)

Klasnja P, Hekler EB, Shiffman S, Boruvka A, Almirall D, Tewari A, Murphy SA. Microrandomized trials: An experimental design for developing just-in-time adaptive interventions. Health Psychol. 2015 Dec;34S(0):1220-8. doi: 10.1037/hea0000305.

Reference Type BACKGROUND
PMID: 26651463 (View on PubMed)

Other Identifiers

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2015P000598

Identifier Type: -

Identifier Source: org_study_id

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