An In Silico Trial to Evaluate Prospectively the Performance of a Radiomics Algorithm for UIP Compared to Medical Doctors

NCT ID: NCT05784207

Last Updated: 2023-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

145 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-06-01

Study Completion Date

2021-12-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to compare AI performance to doctor's performance in the evaluation of IPF/UIP and ILDs without UIP(proven by biopsy).

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Idiopathic Pulmonary Fibrosis Interstitial Lung Disease Radiomics

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

IPF/UIP_CT based

patients with an ILD and a pathological UIP pattern and a final diagnosis of IPF

Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

Intervention Type OTHER

The aim is to evaluate the performance of AI with the performance of doctors

IPF/UIP_Biopsy based

patients with a final diagnosis of IPF but a less typical HRCT pattern( lung biopsy required for the diagnosis)

Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

Intervention Type OTHER

The aim is to evaluate the performance of AI with the performance of doctors

ILD but not IPF and prove by biopsy not UIP

patients with an ILD and a pathological non-UIP pattern

Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

Intervention Type OTHER

The aim is to evaluate the performance of AI with the performance of doctors

Normal

Normal healthy patients

Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

Intervention Type OTHER

The aim is to evaluate the performance of AI with the performance of doctors

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Radiomics model to classify between IPF with UIP pattern and ILDs without UIP pattern

The aim is to evaluate the performance of AI with the performance of doctors

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

\- the availability of non-contrast-enhanced HRCT

Exclusion Criteria

* the use of contrast enhancement
* images containing metal or motion artifacts
* Images reconstructed with a slice thickness larger than 1.5 mm
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Maastricht University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Maastricht University

Maastricht, Limburg, Netherlands

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Netherlands

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

ISTRU

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.