Study on Screening Strategies for Interstitial Lung Abnormalities and Airway Lesions

NCT ID: NCT07023575

Last Updated: 2025-06-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-01

Study Completion Date

2028-11-30

Brief Summary

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The goal of this observational study is to learn about the comorbidity patterns of interstitial and airway abnormalities in adults undergoing health examinations in China. The main questions it aims to answer are:

How do early interstitial lung abnormalities progress to comorbid interstitial and airway diseases? What are the key factors associated with this progression?

Participants undergoing routine health examinations will be assessed for interstitial and airway abnormalities based on imaging and clinical data. Longitudinal follow-up will be used to evaluate disease progression and identify associated risk factors.

Detailed Description

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Conditions

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Interstitial Lung Abnormalities

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Chinese Routine Chest CT Health Examination Cohort

This group includes individuals who underwent routine health examinations with chest CT imaging at participating health checkup centers across China between 2017 and 2024. Participants may have one or more CT records, and no interventions were applied as part of the study. This group will be analyzed for the presence of interstitial lung abnormalities and/or airway diseases based on imaging and lung function data, as well as demographic and clinical characteristics.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Underwent chest CT examination between January 1, 2017 and December 31, 2024
* Age 18 years or older at the time of examination

Exclusion Criteria

\- Missing or incomplete key demographic or imaging information (e.g., missing date of examination, sex, age, or CT report)
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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China-Japan Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Ma Xiao

Chief Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

Site Status

Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

Site Status

Zhongguancun Meinian Health Industry Research Institute

Beijing, , China

Site Status

Central South University

Changsha, , China

Site Status

Affiliated Hospital of Guizhou Medical University

Guiyang, , China

Site Status

Zhejiang University

Hangzhou, , China

Site Status

Henan Provincial People's Hospital

Henan, , China

Site Status

The Affiliated Hospital of Qingdao University

Qingdao, , China

Site Status

The First Affiliated Hospital of China Medical University

Shenyang, , China

Site Status

Henan Hongli Hospital Co., Ltd

Xinxiang, , China

Site Status

Countries

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China

Facility Contacts

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Xianhui Ran, PhD

Role: primary

8613162906826

Role: primary

86-021-64038038

Fang Liu

Role: primary

0731-89753199

Lan Mo

Role: primary

0851-86810999

Jiaojiao Huang

Role: primary

571-87784679

Shaobo Duan

Role: primary

86-0371-65580321

Zixiao Wang

Role: primary

86-024-83283107

Lei Yang

Role: primary

0373-8882111

Other Identifiers

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2024ZD0522301

Identifier Type: -

Identifier Source: org_study_id

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