Fibrotic Interstitial Lung Disease Early Recognition and Strategic Therapy Study in China

NCT ID: NCT06655090

Last Updated: 2024-10-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-12-01

Study Completion Date

2027-11-30

Brief Summary

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This project aimed to: 1) construct a cohort of no less than 10000 cases of f-ILD (including pneumoconiosis ≥3000 cases) with continuous regular follow-up to reveal the clinical phenotypes closely related to the development, progression and prognosis of pulmonary fibrosis; 2) systematically evaluate the safety and effectiveness of frozen lung biopsy, surgical lung biopsy/thoracoscopic lung biopsy and other techniques, and to optimize the histological diagnosis method of f-ILD; 3) construct a set of artificial intelligence (AI) evaluation system for quantitative evaluation of pulmonary fibrosis and its severity, and develop application software; 4) excavate and verify important molecular targets for the formation of pulmonary fibrosis and identify biomarkers; 5) combined with clinical phenotype, imaging, pathology and biomarkers to establish f-ILD early recognition and progress model, intervention strategies, guidelines and consensus, and applicated nationwide.

Detailed Description

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Conditions

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Interstitial Lung Disease (ILD)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Diagnosed as ILD

Exclusion Criteria

* Lack of chest CT
* Patients refused to participant
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First Affiliated Hospital of Guangzhou Medical University

OTHER

Sponsor Role collaborator

Nankai University

OTHER

Sponsor Role collaborator

Jilin University

OTHER

Sponsor Role collaborator

Shanghai Pulmonary Hospital, Shanghai, China

OTHER

Sponsor Role collaborator

Shanghai Chest Hospital

OTHER

Sponsor Role collaborator

Institute of Basic Medical Sciences CAMS

UNKNOWN

Sponsor Role collaborator

Tongji Hospital

OTHER

Sponsor Role collaborator

National Institute for Occupational Health and Poison Control

UNKNOWN

Sponsor Role collaborator

Infervision Medical Technology Company Limited

UNKNOWN

Sponsor Role collaborator

Dai Huaping

OTHER

Sponsor Role lead

Responsible Party

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Dai Huaping

Department of Pulmonary and Critical Care Medicine

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Huaping Dai, M.D. Ph.D.

Role: STUDY_DIRECTOR

China-Japan Friendship Hospital

Locations

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Huaping Dai, M.D. Ph.D.

Role: CONTACT

0086-10-84206271

Facility Contacts

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Huaping Dai, M.D. Ph.D

Role: primary

0086-10-84206271

Other Identifiers

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ChinaJapanFH006

Identifier Type: -

Identifier Source: org_study_id

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