Bipolar Versus Laser Enaculation of Prostate for >80gram Prostate .

NCT ID: NCT05784181

Last Updated: 2024-01-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-01

Study Completion Date

2024-12-01

Brief Summary

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Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser enaculation.

Holmium laser prostatectomy was introduced since 1994 . different types of uses by laser were introduced either resection or enaculation with good outcomes and less complications .

One of the most important issues related to large prostate management is the retreatment after Bipolar resection , another issue that prolonged catheter time post resection .

Detailed Description

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Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser enaculation.

Holmium laser prostatectomy was introduced since 1994 . different types of uses by laser were introduced either resection or enaculation with good outcomes and less complications .

One of the most important issues related to large prostate management is the retreatment after Bipolar resection , another issue that prolonged catheter time post resection , so , we try to analyze the effect of Laser enaculation of the prostate in comparison to Bipolar resection in prostate more than 80 gm .

Aim of the work:

Aim of the work is to compare the efficacy of Bipolar versus Laser enaculation of prostate for \>80gram.

Patients and Methods:

A randomized comparative study will be conducted at Menoufia university hospital , urology department. patients will be selected after informed consent.

Inclusion criteria: similar for all patients prostatic volume more than 80 gm , peak urinary flow rate measurement (Qmax) \<15 ml/s, International Prostate Symptom Score (IPSS) of \>8 , postvoid residual (PVR) \<400 ml.

Exclusion criteria: Patients with prostate size less than 80gm , urethral stricture, acute urinary tract infection, repeated treatment .

Preoperatively, all the patients will undergo thorough process of history taking , clinical examination, and investigations in the form of abdominopelvic and trans rectal ultrasonography , PSA ,urine analysis, urine culture if needed and routine pre-operative lab investigations as (CBC , PT, LFTs, serum creatinine and RBS).

The treatment modality chosen for an individual will be randomized . All patients with positive urine culture will be treated by proper antibiotics before the procedures.

Peri-operatively , all patients will receive a single shot of pre-operative antibiotic.

For the first group patients transurethral resection of prostate For the second group patients Laser enaculation by holmium: YAG laser Postoperatively, patients will undergo IPSS score , flowmetry post operative after 3months .

Conditions

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Bipolar TURP , Laser Enucleation in Management of Enlarged Prostate

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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patients prostatic volume more than 80 gm turp by bipolar resection

pt with 80gm prostate size underwent bipolar resection

Group Type OTHER

bipolar transurethral resection and Laser enaculation by holmium: YAG laser

Intervention Type DEVICE

Laser enaculation by holmium: YAG laser

patients prostatic volume more than 80 gm turp by Laser enaculation by holmium: YAG laser

pt with 80gm prostate size underwent Laser enaculation by holmium: YAG laser

Group Type OTHER

bipolar transurethral resection and Laser enaculation by holmium: YAG laser

Intervention Type DEVICE

Laser enaculation by holmium: YAG laser

Interventions

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bipolar transurethral resection and Laser enaculation by holmium: YAG laser

Laser enaculation by holmium: YAG laser

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

\- similar for all patients prostatic volume more than 80 gm , peak urinary flow rate measurement (Qmax) \<15 ml/s, International Prostate Symptom Score (IPSS) of \>8 , postvoid residual (PVR) \<400 ml

Exclusion Criteria

* Patients with prostate size less than 80gm , urethral stricture, acute urinary tract infection, repeated treatment .
Minimum Eligible Age

40 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Menoufia University

OTHER

Sponsor Role lead

Responsible Party

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Hossam Kandeel

Yassin Abdel Ghaffar St- from Gamal Abdel Anasar St - Faculty of Medicine.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Medicine

Shibīn al Kawm, Menoufia -, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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mohamed kamal omar, MD

Role: CONTACT

00201066949454

hossam elsaid kandeel, master

Role: CONTACT

00201097991198

Other Identifiers

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2-2022

Identifier Type: -

Identifier Source: org_study_id

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