The IGNITE for Kids Study on Concentrated Investment in Black Neighborhoods and Child Health and Well-Being

NCT ID: NCT05760001

Last Updated: 2025-09-26

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 221 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2023-06-10
• Study Completion Date: 2026-02-17

Brief Summary

Black children and adults in the United States fare worse across nearly every health indicator compared to White individuals. In Philadelphia, the location of this study, these health disparities result in a stark longevity gap, with average life expectancies in poor, predominantly Black neighborhoods being 20 years lower than in nearby affluent, predominantly White neighborhoods. The investigators will conduct a cluster randomized controlled trial (RCT) of a suite of place- based and financial-wellbeing interventions at the community, organization, and individual/household levels that address the social determinants of racial health disparities. At the community level, the investigators address underinvestment in Black neighborhoods by implementing vacant lot greening, abandoned house remediation, tree planting, and trash cleanup. At the organization level, the investigators partner with community-based financial empowerment providers to develop cross-organizational infrastructure to increase reach and maximize efficiency. At the individual/household levels, the investigators increase access to public benefits, financial counseling and tax preparation services, and emergency cash assistance. The investigators will test this "big push" intervention in 60 Black neighborhood micro-clusters, with a total of 480 children. The investigators hypothesize that this "big push" intervention will have significant impact on children's health and wellbeing.

Detailed Description

Black individuals in the United States fare worse than White individuals across almost every social, economic, and health indicator. The Black health disadvantage starts at birth, reflecting the cumulative toll of racialized social stressors and healthcare discrimination on maternal health and resulting in higher rates of pre-term birth and low birth weight. Black youth are disproportionately exposed to environmental toxins such as lead and adverse childhood events such as financial hardship and neighborhood violence. Black children also have higher rates of chronic disease, including asthma and diabetes. These and other forces result in inequities in child health and well-being and can also impact children's educational and earning potential. Furthermore, these inequities culminate in a stark racial longevity gap: in Philadelphia, the location of this study, life expectancy for people living in a poor, predominantly Black neighborhood is 20 years lower than for people living in a nearby affluent, predominantly White neighborhood.

The fundamental cause of these striking and pervasive disparities is structural racism - the confluence of deep historical, institutional, cultural, and ideological forces that unequally distribute resources and risks across racialized groups. Structural racism patterns health by affecting a range of interconnected, mutually reinforcing social determinants of health at the national, neighborhood, household, and individual levels. Most notably, longstanding, systematic disinvestment has resulted in highly segregated Black neighborhoods with dilapidated environmental conditions and severe economic insecurity within Black households, leading to a "feedback loop of concentrated racial disadvantage," all of which have been strongly tied to poor health.

Most interventions seeking to address racial health disparities focus on individual-level behaviors and outcomes, or individual channels by which structural racism harms health. However, by failing to address upstream social determinants, these interventions have had limited population level impact. A multi-level, multi-component intervention package focused on a range of social determinants of health is necessary to meaningfully address structural racism as a fundamental cause of racial health disparities. In this trial, we aim to implement such a multi-level, multi-component intervention and then evaluate its impact on child health and well-being.

Conditions

Financial Stress; Economic Problems; Environmental Exposure; Health Behavior; Health, Subjective; Mental Health Wellness

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Intervention Arm

At the individual level, participants in the intervention arm will receive place-based and financial well-being interventions.

These will include, at the individual level:

• Tax preparation
• Access to public benefits
• Financial counseling and microgrants

At the neighborhood level:

• Abandoned house remediation
• Trash cleanup
• Vacant lot greening
• Tree planting

Group Type: EXPERIMENTAL

Assigned Interventions

Intervention Type: OTHER

Financial well-being interventions:

• Tax preparation; access to public benefits; financial counseling and microgrants

Place-based interventions:

• Vacant lot greening; abandoned house remediation; trash cleanup; tree planting

Control Arm

Participants in the control arm will not receive any of the listed interventions

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Assigned Interventions

Financial well-being interventions:

• Tax preparation; access to public benefits; financial counseling and microgrants

Place-based interventions:

• Vacant lot greening; abandoned house remediation; trash cleanup; tree planting

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Child is between the ages of 3 and 17 years at the start of the trial (between the ages of 5 and 19 years at the end of the trial)
• Parent/caregiver is at least 18 years of age
• Parent/caregiver has the ability to communicate via text messaging
• Parent/caregiver is comfortable communicating in English
• Child is a permanent resident of the home where they are to be enrolled
• Parent/caregiver has knowledge of their household finances

Exclusion Criteria

• Children who plan to move out of the study microcluster within 6 months
• Children whose caregivers are unable to fully consent and participate based on CC team assessment

• Minimum Eligible Age: 3 Years
• Maximum Eligible Age: 19 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Children's Hospital of Philadelphia

OTHER

Sponsor Role: collaborator

University of Pennsylvania

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Atheendar Venkataramani, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Eugenia South, MD, MSHP

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Aditi Vasan, MD, MSHP

Role: PRINCIPAL_INVESTIGATOR

Children's Hospital of Philadelphia

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, United States

Countries

United States

Provided Documents

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

850178b

Identifier Type: -

Identifier Source: org_study_id