Establishment of a Method for Extraction and Quantification of Gingival Tissue Nicotine y

NCT ID: NCT05736250

Last Updated: 2023-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-01-14

Study Completion Date

2023-06-30

Brief Summary

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establishment of a method for extraction and quantification of gingival tissue nicotine in relation to conventional tobacco biomarkers: a pilot study

Detailed Description

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The study aim to establish a method for extraction and quantification of gingival tissue nicotine. Additionnaly, the relationship between the nicotine tissue intoxication with others smoking indicators will be evaluated as mentionned in the following PICO question:

* P: Smoker patients
* I: Biopsie of gingival tissue
* C: Non-smoker patient
* O: nicotine dependence test (FTND), salivary cotinine, fibroblast nicotine, number of cigarette consumed per day (NCC) and the pack-year (PY)

Conditions

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Smoking, Cigarette

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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TEST group

smoker patients

biopsie

Intervention Type DIAGNOSTIC_TEST

gingival biopsie

Interventions

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biopsie

gingival biopsie

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* non smokers
* smokers

Exclusion Criteria

* not able to have biopsie
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Leila Salhi

PhD, head of clinic, Department of periodontology, buccal surgery and buccal implantology,

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Salhi

Liège, Liege, Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Leila Salhi, PhD

Role: CONTACT

003243233123

Facility Contacts

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Leila Salhi, PhD

Role: primary

Other Identifiers

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2021:250

Identifier Type: -

Identifier Source: org_study_id

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