Tobacco Use in Pregnancy Intervention for Cessation

NCT ID: NCT03442530

Last Updated: 2020-03-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-22

Study Completion Date

2019-02-15

Brief Summary

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The proposed project will test the effectiveness of the novel delivery of an established tobacco cessation treatment among pregnant women in Kentucky. Tobacco use during pregnancy is one of the most modifiable risk factors associated with poor birth and maternal outcomes and yet smoking prevalence among pregnant women in Kentucky is among the highest in the county and estimated to be twice that of the national average, with no meaningful declines observed in twenty years.

Detailed Description

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The purpose of this pilot project is to test effectiveness of a tobacco-treatment cessation intervention (American College of Obstetricians and Gynecologists (ACOG) 5 A's) through use of a non-physician healthcare champion from within the clinic's existing infrastructure. This Tobacco use in Pregnancy Intervention for Cessation (ToPIC) will involve training the identified healthcare provider to become a Certified Tobacco Treatment Specialist (CTTS) and to administer the 5 A's to pregnant Medicaid patients receiving prenatal care through two high-volume Kentucky obstetrics clinics. This trial will provide evidence to evaluate this approach to delivering an established intervention in clinical practice.

The Investigators propose to test the effectiveness of the clinical intervention by using a two-armed cluster randomized controlled design. Eligible participants will be randomized to the intervention (ToPIC) or standard of care for smoking cessation in pregnancy. This pilot project will gather quantitative and qualitative data for a mixed-method, multi-stakeholder process evaluation of intervention training and delivery. Furthermore, the Investigators' use of Medicaid claims data to examine healthcare utilization outside of maternal and infant well-care visits will enhance understanding of the strengths and limitations of these data for future evaluations. This study has the potential to significantly impact the most vulnerable in Kentucky, where rates of tobacco use among pregnant women are among the highest in the nation.

Conditions

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Pregnancy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Tobacco Treatment As Usual (TTAU)

Eligible women assigned to the control group will be informed of the risks of tobacco use and benefits of quitting using the ACOG 5A's approach by their healthcare provider.5 This standard takes approximately 5-15 minutes, and is offered at each prenatal and postpartum appointment. The study coordinator will invite participants to complete the tobacco use questionnaires (TUQ),urine cotinine validation, and Expired Air Carbon Monoxide (EACO) analysis to assess ongoing tobacco use at the designated time points.

Group Type ACTIVE_COMPARATOR

Tobacco Treatment As Usual (TTAU)

Intervention Type BEHAVIORAL

Standard of care tobacco cessation counseling for pregnant women

ToPIC

Eligible women assigned to the intervention will receive TTAU plus ToPIC administered by the CTTS. At least once monthly, at routinely scheduled prenatal visits or through telephone, the CTTS will provide cessation counseling. The CTTS will invite participants to complete TUQs,urine cotinine validation and EACO analysis to assess ongoing tobacco use at the designated time points.

Group Type EXPERIMENTAL

ToPIC

Intervention Type BEHAVIORAL

Expanded tobacco cessation counseling for pregnant women.

Interventions

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ToPIC

Expanded tobacco cessation counseling for pregnant women.

Intervention Type BEHAVIORAL

Tobacco Treatment As Usual (TTAU)

Standard of care tobacco cessation counseling for pregnant women

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* pregnant
* tobacco user
* able to read and write English
* Medicaid eligible

Exclusion Criteria

* male
Minimum Eligible Age

18 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Kentucky

OTHER

Sponsor Role collaborator

Kristin Ashford

OTHER

Sponsor Role lead

Responsible Party

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Kristin Ashford

Associate Dean of Undergraduate Faculty Affairs, University of Kentucky College of Nursing

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Kristin Ashford

Role: PRINCIPAL_INVESTIGATOR

University of Kentucky

Locations

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University of Kentucky College of Nursing

Lexington, Kentucky, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Informed Consent Form

View Document

Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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17-0658-P3K

Identifier Type: -

Identifier Source: org_study_id

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