Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
182 participants
OBSERVATIONAL
2021-07-22
2025-12-31
Brief Summary
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Detailed Description
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Examine the short-term impacts of vaping on pulmonary and respiratory outcomes.
OUTLINE:
Current e-cigarette users will vape their own e-cigarette device ad libitum for 30 minutes; non-users will watch a neutral video for 30 minutes. Before and after the 30 minute vaping \[video\] session, participants will undergo the following assessments: computer-based spirometry testing, nitric oxide breath testing, airwave oscillometry, and an assessment of endothelial function. Participants will also undergo collection of blood.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Prevention (survey, breathe tests, biospecimen collection)
Participants undergo computer-based spirometry testing, nitric oxide breath testing, airwave oscillometry, and an assessment of endothelial function. Participants will undergo collection of blood. Current e-cigarette users also vape their own e-cigarette device for 30 minutes.
Biospecimen Collection
Undergo collection of blood
Nitric Oxide Breath Test
Undergo nitric oxide breath testing
Oscillometry
Undergo airwave oscillometry
Spirometry
Undergo spirometry
Survey Administration
Complete survey
Endothelial function
Endothelial function will be assessed with the EndoPAT device, which measures changes in pressure from sensors placed on the fingertip
Interventions
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Biospecimen Collection
Undergo collection of blood
Nitric Oxide Breath Test
Undergo nitric oxide breath testing
Oscillometry
Undergo airwave oscillometry
Spirometry
Undergo spirometry
Survey Administration
Complete survey
Endothelial function
Endothelial function will be assessed with the EndoPAT device, which measures changes in pressure from sensors placed on the fingertip
Eligibility Criteria
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Inclusion Criteria
* No self-reported diagnosis of lung disease (e.g., coronavirus disease-2019 \[COVID-19\], pneumonia, cystic fibrosis)
* No history of cardiac event or distress
* Not currently breastfeeding, pregnant, or planning to become pregnant (e-cig users only; will be confirmed via pregnancy test)
15 Years
25 Years
ALL
Yes
Sponsors
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Ohio State University Comprehensive Cancer Center
OTHER
Responsible Party
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Megan Roberts
Principal Investigator
Principal Investigators
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Megan E Roberts, PhD
Role: PRINCIPAL_INVESTIGATOR
Ohio State University Comprehensive Cancer Center
Locations
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Countries
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Related Links
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The Jamesline
Other Identifiers
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NCI-2021-06438
Identifier Type: REGISTRY
Identifier Source: secondary_id
OSU-20320
Identifier Type: -
Identifier Source: org_study_id
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