Young Adults' Reactions to Low Nicotine Cigarette Advertising

NCT ID: NCT04906148

Last Updated: 2024-10-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 56 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-05-27
• Study Completion Date: 2023-08-11

Brief Summary

Reducing the nicotine content in combustible cigarettes to non-addictive levels has demonstrated promise as a safe and effective public health strategy for decreasing tobacco-caused morbidity and mortality. Little data are available, however, assessing how the marketing of low nicotine content (LNC) cigarettes could dampen their potential population health benefit. This study will examine LNC cigarette advertising content effects on message recall, viewing patterns, product perceptions, and use behaviors. Young adults (N = 340; 170 smokers, 170 non-smokers) will complete a single-session laboratory study using a 2 x 2 between-subject design to manipulate advertisement messaging accuracy (true vs. false/misleading) and content (implicit vs. explicit). Findings may be used to guide public health policy decisions related to regulating cigarette nicotine content and marketing.

Conditions

Smoking

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: FACTORIAL
• Primary Study Purpose: OTHER
• Blinding Strategy: SINGLE

Study Groups

Smokers

Smokers will be randomized to view an advertisement with either true or misleading and implicit or explicit harm messaging content.

Group Type: EXPERIMENTAL

Advertisement content (explicit vs. implicit)

Intervention Type: OTHER

Participants will be randomly assigned to view an advertisement with either implicit or explicit harm messaging content

Advertisement content (true vs. misleading)

Intervention Type: OTHER

Participants will be randomly assigned to view an advertisement with either true or misleading messaging content

Non-smokers

Non-smokers will be randomized to view an advertisement with either true or misleading and implicit or explicit harm messaging content.

Group Type: EXPERIMENTAL

Advertisement content (explicit vs. implicit)

Intervention Type: OTHER

Participants will be randomly assigned to view an advertisement with either implicit or explicit harm messaging content

Advertisement content (true vs. misleading)

Intervention Type: OTHER

Participants will be randomly assigned to view an advertisement with either true or misleading messaging content

Interventions

Advertisement content (explicit vs. implicit)

Participants will be randomly assigned to view an advertisement with either implicit or explicit harm messaging content

Intervention Type: OTHER

Advertisement content (true vs. misleading)

Participants will be randomly assigned to view an advertisement with either true or misleading messaging content

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Aged 21-29
• Able to use a computer or related technology (such as a smartphone or tablet) with reliable internet access and willing to use the device to participate in the research study.
• Have a valid email address and willing to use email to participate in the research study. Participants without an existing email account who are willing to create one for study purposes are eligible to participate.

Exclusion Criteria

• Currently enrolled in a cessation program
• Report consuming ≥ 25 alcohol-containing drinks per week
• Report a history or current psychiatric diagnosis or severe medical condition
• Are color-blind or have another visual impairment (e.g., partial blindness, uncorrected cataract)
• Self-report being pregnant and/or lactating
• Are diagnosed with or test positive for COVID-19. Participants who report having traveled to a high-risk area in the past 2 weeks or who have been in close contact with someone confirmed or being evaluated for COVID-19 will be placed on a waitlist. Waitlisted participants will be asked to self-isolate for 14 days after exposure (even without symptoms) and will be re-screened for eligibility post self-isolation.

Additional, general reasons for exclusion include:

• Significant non-compliance with protocol and/or study design as determined by the Principal Investigator (PI) at any point throughout the study.
• Past, current, anticipated, or pending enrollment in another research program over the study period that could potentially impact study data as determined by the PI.
• Any medical condition, illness, disorder, adverse event (AE), or concomitant medication that could compromise participant safety or significantly impact study performance as determined by the PI. Subjects may be deemed ineligible for any of the aforementioned reasons at any point throughout the study, as well as during the initial telephone screen.

• Minimum Eligible Age: 21 Years
• Maximum Eligible Age: 29 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Cancer Institute (NCI)

NIH

Sponsor Role: collaborator

Abramson Cancer Center at Penn Medicine

OTHER

Sponsor Role: lead

Responsible Party

Andrew Strasser

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Andrew Strasser, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Pennsylvania

Locations

Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania

Philadelphia, Pennsylvania, United States

Countries

United States

Other Identifiers

K07CA218366

Identifier Type: NIH

Identifier Source: secondary_id

View Link

844887

Identifier Type: OTHER

Identifier Source: secondary_id

UPCC 03021

Identifier Type: -

Identifier Source: org_study_id