Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

82 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-01

Study Completion Date

2021-12-31

Brief Summary

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Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones

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Detailed Description

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Conditions

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Renal Stone

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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ESWL alone

Extracorporeal shock wave lithotripsy will be given to the patient

Group Type ACTIVE_COMPARATOR

Extracorporeal shock wave lithotripsy

Intervention Type PROCEDURE

Extracorporeal shock wave lithotripsy will given to the patients

ESWL combined with tamsulosin therapy

Extracorporeal shock wave lithotripsy combined with tamsulosin therapy will be given to the patient

Group Type ACTIVE_COMPARATOR

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.

Intervention Type PROCEDURE

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients

Interventions

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Extracorporeal shock wave lithotripsy

Extracorporeal shock wave lithotripsy will given to the patients

Intervention Type PROCEDURE

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.

Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* single upper ureteric stone
* size ranging from 6-15 mm
* stones history less than 6 months

Exclusion Criteria

* Patients with urinary tract infection
* multiple ureteric stones,
* presence of a ureteric stricture distal to the stone,
* previous unsuccessful ESWL,
* concomitant use of calcium channel blockers or alpha-adrenergic antagonists
* patients with abnormal coagulation profile

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No