Optimizing Attention and Sleep Intervention Study

NCT ID: NCT05683756

Last Updated: 2025-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-01

Study Completion Date

2026-12-31

Brief Summary

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The goal of this pilot clinical effectiveness trial is to compare a brief parent behavioral intervention (PBI) to a modified sleep focused PBI (SF-PBI) delivered by therapists in pediatric primary care for families of children 3-5 years old with sleep problems and early ADHD symptoms.

The main aims are to:

Aim 1: Demonstrate the acceptability, feasibility, and appropriateness of the sleep focused PBI (SF-PBI) delivered in pediatric primary care for preschool-aged children (3-5 years old) at elevated risk for ADHD.

Aim 2: Examine change in target engagement (sleep) and ADHD symptoms among preschool-aged children at elevated risk for ADHD receiving SF-PBI compared to standard PBI.

Detailed Description

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Sleep problems may be one mechanism through which young children may be at risk for developing ADHD, although first line ADHD interventions, including parent behavioral interventions (PBIs), do not address sleep. Investigators will test a modified version of a PBI to target sleep disrupting behaviors for children 3-5 years old at elevated risk for ADHD. The intervention will be delivered by behavioral health therapists embedded in pediatric primary care to increase families' access to intervention. This pilot effectiveness trial is the first step towards developing an early intervention targeting sleep as a mechanism to reduce the prevalence, symptoms, and impairments associated with childhood ADHD.

Conditions

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Attention Deficit and Disruptive Behavior Disorders Attention Deficit Hyperactivity Disorder Child, Preschool Sleep Sleep Disturbance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Brief Parent Behavioral Intervention

A brief parent behavioral intervention with evidenced based strategies for treatment of ADHD.

Group Type ACTIVE_COMPARATOR

Brief Parent Behavioral Intervention

Intervention Type BEHAVIORAL

PBI administered in pediatric primary care by an embedded therapist.

Sleep-Focused Parent Behavioral Intervention

A modified version of the brief parent behavioral intervention that specifically targets sleep disrupting behaviors.

Group Type EXPERIMENTAL

Sleep-Focused Parent Behavioral Intervention

Intervention Type BEHAVIORAL

SF-PBI administered in pediatric primary care by an embedded therapist.

Interventions

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Brief Parent Behavioral Intervention

PBI administered in pediatric primary care by an embedded therapist.

Intervention Type BEHAVIORAL

Sleep-Focused Parent Behavioral Intervention

SF-PBI administered in pediatric primary care by an embedded therapist.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Parent/Caregiver:

* (1) Legal guardian is at least 18 years of age
* (2) Reads and speaks English

Child:

* (1) 3-5 years of age
* (2) Caregiver report of 4 or more ADHD symptoms
* (3) Caregiver reports child's sleep as a "moderate" or "serious problem"
* (4) English speaking
* (5) Child receives care from participating pediatric primary care office

Exclusion Criteria

* (1) Sleep interfering medical diagnoses (e.g., narcolepsy, obstructive sleep apnea)
* (2) Severe neurodevelopmental disorder
Minimum Eligible Age

3 Years

Maximum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

University of Pittsburgh

OTHER

Sponsor Role lead

Responsible Party

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Heather Joseph

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Heather M Joseph, DO

Role: PRINCIPAL_INVESTIGATOR

Assistant Professor of Psychiatry and Pediatrics, University of Pittsburgh

Locations

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Children's Community Pediatrics Bass Wolfson, Cranberry

Cranberry Township, Pennsylvania, United States

Site Status RECRUITING

Children's Community Pediatrics GIL Murrysville

Monroeville, Pennsylvania, United States

Site Status RECRUITING

Children's Community Pediatrics Shenango

New Castle, Pennsylvania, United States

Site Status RECRUITING

Children's Community Pediatrics Neshannock

New Castle, Pennsylvania, United States

Site Status NOT_YET_RECRUITING

Children's Community Pediatrics GIL East Liberty

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Children's Community Pediatrics Bass Wolfson, Squirrel Hill

Pittsburgh, Pennsylvania, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Heather M Joseph, DO

Role: CONTACT

4122465338

References

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Cunningham CE, Bremner R, Boyle M. Large group community-based parenting programs for families of preschoolers at risk for disruptive behaviour disorders: utilization, cost effectiveness, and outcome. J Child Psychol Psychiatry. 1995 Oct;36(7):1141-59. doi: 10.1111/j.1469-7610.1995.tb01362.x.

Reference Type BACKGROUND
PMID: 8847377 (View on PubMed)

Joseph HM, Levenson JC, Conlon RPK, Mannion K, Kipp HL, Gradian A, Wallace ML, Williamson AA. Optimizing Attention and Sleep Intervention Study (OASIS): a protocol for a pilot randomized controlled trial to compare parent behavioral interventions with and without sleep strategies delivered in pediatric primary care for preschool-aged children at risk of childhood ADHD. Pilot Feasibility Stud. 2025 Feb 25;11(1):22. doi: 10.1186/s40814-025-01600-0.

Reference Type RESULT
PMID: 40001155 (View on PubMed)

Other Identifiers

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R34MH131993

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY22070096

Identifier Type: -

Identifier Source: org_study_id

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