Fistula-in-ano in Infants and Children

NCT ID: NCT05666609

Last Updated: 2025-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2027-12-31

Brief Summary

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In this prospective, randomized trail, duration of non-cutting seton placement in patients with fistula-in-ano is evaluated.

Detailed Description

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In this prospective, randomized trail, patients are treated in case of fistula-in-ano with non-cutting seton placement. They are then randomized 1:1 in either Group A (duration of placed seton for 4 weeks) or Group B (duration of placed seton for 12 weeks). Patients are participating after informed consent is obtained.

Conditions

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Fistula in Ano

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Group A: duration of placed seton 4 weeks Group B: duration of placed seton 12 weeks
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Masking is not possible due to study design.

Study Groups

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Group 4weeks

Duration of placed seton 4 weeks

Group Type ACTIVE_COMPARATOR

placement of non-cutting seton (silicone)

Intervention Type PROCEDURE

Treatment of Fistula in ano is conducted according to the institution's treatment guidelines. Silicon seton placement is conducted under general anesthesia. Identification of the FIA is secured by the insertion of a bulb-headed lacrimal probe, on which a silicon vessel loop is attached and pulled through the entire fistulous tract. In case of a perianal abscess, drainage and sphincter-sparing debridement is performed followed by secondary wound healing. The loop is ligated loosely outside the anus without any additional tension to the skin. Duration of placed seton is depending on group assignment and is set to either 4 or 12 weeks.

Group 12weeks

Duration of placed seton 12 weeks

Group Type ACTIVE_COMPARATOR

placement of non-cutting seton (silicone)

Intervention Type PROCEDURE

Treatment of Fistula in ano is conducted according to the institution's treatment guidelines. Silicon seton placement is conducted under general anesthesia. Identification of the FIA is secured by the insertion of a bulb-headed lacrimal probe, on which a silicon vessel loop is attached and pulled through the entire fistulous tract. In case of a perianal abscess, drainage and sphincter-sparing debridement is performed followed by secondary wound healing. The loop is ligated loosely outside the anus without any additional tension to the skin. Duration of placed seton is depending on group assignment and is set to either 4 or 12 weeks.

Interventions

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placement of non-cutting seton (silicone)

Treatment of Fistula in ano is conducted according to the institution's treatment guidelines. Silicon seton placement is conducted under general anesthesia. Identification of the FIA is secured by the insertion of a bulb-headed lacrimal probe, on which a silicon vessel loop is attached and pulled through the entire fistulous tract. In case of a perianal abscess, drainage and sphincter-sparing debridement is performed followed by secondary wound healing. The loop is ligated loosely outside the anus without any additional tension to the skin. Duration of placed seton is depending on group assignment and is set to either 4 or 12 weeks.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* any patient with FIA and treatment with non-cutting seton placement in our institution
* regardless of underlying diagnoses
* age 0-18 years

Exclusion Criteria

* none
Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Friedrich-Alexander-Universität Erlangen-Nürnberg

OTHER

Sponsor Role lead

Responsible Party

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Dr. med. Sonja Diez

Medical Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sonja Diez, MD

Role: PRINCIPAL_INVESTIGATOR

Friedrich-Alexander-Universität Erlangen-Nürnberg

Locations

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Friedrich-Alexander-Universität Erlangen-Nürnberg, Pediatric Surgery

Erlangen, Bavaria, Germany

Site Status RECRUITING

Countries

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Germany

Central Contacts

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Sonja Diez, MD

Role: CONTACT

004991318532923

Manuel Besendörfer, MD

Role: CONTACT

004991318532923

Facility Contacts

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Sonja Diez, M.D.

Role: primary

0049 09131 85 32923

Other Identifiers

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FIA2023-7

Identifier Type: -

Identifier Source: org_study_id

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