PRP Use in Treatment of Fistula Ano

NCT ID: NCT04187651

Last Updated: 2025-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-20

Study Completion Date

2025-12-01

Brief Summary

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In treatment of perianal fistula several methods are described. However, since the Hippocrates basics of surgical treatment has not changed very much. the aim of this study is to evaluate the effectiveness of PRP gel in treatment of perianal fistula.

Detailed Description

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Perianal fistula is a chronic condition that seriously affects the patients' quality of life. There are different treatment modalities used in treatment. Recently sphincter preserving methods are becoming more popular with low complication rates. Most of this methods aiming the closure of fistula tract by different pathways.

Platelet rich plasma (PRP) is used in a wide range of conditions in medicine. The investigator's team showed the effective treatment of pilonidal disease by use of PRP gel. In the recent study, aim to evaluate the effectiveness of PRP gel in treatment of perianal fistula.

Patients with perianal fistula will be evaluated for the study. After taking permission with informed consent; cases will be included in the study. Cases with inflammatory bowel disease, platelet function disorders or connective tissue disorders that may alter wound healing will be excluded from the study.

After, PRP application to the fistula tract patients will be taken to follow up. Perianal fistulas will be followed by magnetic resonance imaging 1 month after the application. Pre-application and post-application scans will be used for the evaluation of the treatment success.

Conditions

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Fistula in Ano

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

PRP gel will be applicated to all cases
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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PRP gel application

PRP application for perianal fistula

Group Type EXPERIMENTAL

platelet rich plasma

Intervention Type OTHER

platelet rich plasma prepared from the patients' own blood will be applied to the fistula tract

Interventions

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platelet rich plasma

platelet rich plasma prepared from the patients' own blood will be applied to the fistula tract

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients with perianal fistula
* signing the informed consent form
* above the age of 18

Exclusion Criteria

* inflammatory bowel disease
* previous radiation therapy
* having connective tissue disorders
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uşak University

OTHER

Sponsor Role lead

Responsible Party

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Barış Sevinç

Assoc. Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Barış Sevinç, M.D.

Role: PRINCIPAL_INVESTIGATOR

Uşak University Medical School

Locations

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Uşak University

Uşak, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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PRPF

Identifier Type: -

Identifier Source: org_study_id

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