AHC Ballana Heart Study

NCT ID: NCT05661318

Last Updated: 2024-05-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2055-01-31

Brief Summary

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This Study is designed to assess CVD incidence, prevalence, progression and related risk factors, including genetic background. It will provide an important base for all cardiovascular research activities in our centre and help in designing future studies and guide policy.

Detailed Description

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Background Population-based longitudinal studies are a cornerstone in understanding current disease landscapes affecting communities and collecting reliable data to guide prevention and treatment strategies. In Egypt there is pressing need of collecting reliable data on cardiovascular disease (CVD) in defined populations.

Objectives Defining the cardiovascular phenotype, genotype as well as OMICS and risk factors for CVD in a defined population in Egypt with follow up for up to 30 years

Methods As a first step, a random representative sample of 1,200 households from the Ballana population will be created. Following inclusion, patients will be screened for their cardiovascular profile and followed up for changes in their profile and cardiovascular events continuously every year in high risk patients and every 3 years for the rest of the participants for a period of 30 years.

Conditions

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Genetic Predisposition to Disease

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Study Groups

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BHS

Residents of Ballana from the 1,200 randomly selected households

Risk assessment

Intervention Type OTHER

Collect clinical, laboratoary and genetics data from the participants after informed consent

Interventions

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Risk assessment

Collect clinical, laboratoary and genetics data from the participants after informed consent

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Residents of Ballana from the 1,200 randomly selected households
* Participants must have a valid National ID card
* Written informed consent

Exclusion Criteria

• Residents who are younger than 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Magdi Yacoub Heart Foundation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Magdi H Yacoub, FRS OM

Role: PRINCIPAL_INVESTIGATOR

Imperial College London, and Magdi Yacoub Heart Foundation

Locations

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Aswan Heart Centre - Magdi Yacoub Heart Foundation

Aswān, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Yasmine Aguib, PhD

Role: CONTACT

+201092036368

Ahmed Elguindy, MD

Role: CONTACT

+201001615151

Facility Contacts

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Ahmed M ElGuindy, MD, MRCP

Role: primary

+201001615151

Shehab M Anwer, MD

Role: backup

+41788816333

References

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Keates AK, Mocumbi AO, Ntsekhe M, Sliwa K, Stewart S. Cardiovascular disease in Africa: epidemiological profile and challenges. Nat Rev Cardiol. 2017 May;14(5):273-293. doi: 10.1038/nrcardio.2017.19. Epub 2017 Feb 23.

Reference Type BACKGROUND
PMID: 28230175 (View on PubMed)

Other Identifiers

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AHC-BHS

Identifier Type: -

Identifier Source: org_study_id

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