Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study
NCT ID: NCT00497887
Last Updated: 2010-10-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
4000 participants
OBSERVATIONAL
2006-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Acute myocardial infarction
* Inability to give informed consent
18 Years
85 Years
ALL
No
Sponsors
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University of Leipzig
OTHER
Responsible Party
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University Leipzig
Principal Investigators
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Joachim Thiery, MD PhD
Role: PRINCIPAL_INVESTIGATOR
University of Leipzig
Locations
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University of Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics
Leipzig, , Germany
University of Leipzig, Heart Center, Department of Cardiology
Leipzig, , Germany
Countries
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Central Contacts
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Facility Contacts
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Gerhard Schuler, MD PhD
Role: primary
Stephan Gielen, MD PhD
Role: backup
References
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Teren A, Vogel A, Beutner F, Gielen S, Burkhardt R, Scholz M, Thiery J, Ceglarek U. Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease. Nutr Metab Cardiovasc Dis. 2020 Sep 24;30(10):1662-1672. doi: 10.1016/j.numecd.2020.05.031. Epub 2020 Jun 8.
Jacobi T, Massier L, Kloting N, Horn K, Schuch A, Ahnert P, Engel C, Loffler M, Burkhardt R, Thiery J, Tonjes A, Stumvoll M, Bluher M, Doxiadis I, Scholz M, Kovacs P. HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes. J Clin Endocrinol Metab. 2020 Mar 1;105(3):dgaa027. doi: 10.1210/clinem/dgaa027.
Pott J, Schlegel V, Teren A, Horn K, Kirsten H, Bluecher C, Kratzsch J, Loeffler M, Thiery J, Burkhardt R, Scholz M. Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. Circ Genom Precis Med. 2018 May;11(5):e001992. doi: 10.1161/CIRCGEN.117.001992.
Weissgerber A, Scholz M, Teren A, Sandri M, Teupser D, Gielen S, Thiery J, Schuler G, Beutner F. The value of noncoronary atherosclerosis for identifying coronary artery disease: results of the Leipzig LIFE Heart Study. Clin Res Cardiol. 2016 Feb;105(2):172-81. doi: 10.1007/s00392-015-0900-x. Epub 2015 Sep 11.
Beutner F, Teupser D, Gielen S, Holdt LM, Scholz M, Boudriot E, Schuler G, Thiery J. Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease. PLoS One. 2011;6(12):e29070. doi: 10.1371/journal.pone.0029070. Epub 2011 Dec 22.
Related Links
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University Hospital Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics
Other Identifiers
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276-2005
Identifier Type: -
Identifier Source: org_study_id