Observational Study of Exposure to Environmental Toxicants Among Firefighters

NCT ID: NCT05643014

Last Updated: 2025-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-02-01

Study Completion Date

2026-12-31

Brief Summary

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Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.

Detailed Description

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Conditions

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Healthy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Firefighters over 18 years old

This is a within subject, observational study of firefighters. This study will involve three sample collections including buccal cells and urine samples; one collection pre and two collections post-structural fire exposure.

Sample collection

Intervention Type OTHER

This study will involve three sample collections including buccal cells and urine samples

Interventions

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Sample collection

This study will involve three sample collections including buccal cells and urine samples

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Firefighter (career or volunteer)
* Over 18 years of age
* Able to provide written voluntary consent

Exclusion Criteria

* Unwilling to provide a pre and post-exposure urine sample
* Current cancer diagnosis
* Tobacco use within the last 1 year (verified by urinary TNEs)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Masonic Cancer Center, University of Minnesota

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Masonic Cancer Center

Minneapolis, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Joni Jensen

Role: CONTACT

612-624-5178

Facility Contacts

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Stephen S Hecht

Role: primary

612-624-7604

Joni A Jensen

Role: backup

+1 612-624-7604

Other Identifiers

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2018NTLS135

Identifier Type: -

Identifier Source: org_study_id

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