Effects of Prone Position After Major Abdominal Surgery

NCT ID: NCT05630443

Last Updated: 2024-05-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-01

Study Completion Date

2026-12-31

Brief Summary

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Evaluation of postoperative prone position after major abdominal surgery. A randomized clinical trial of 100+100 patients and further add a voice/speech/singing protocol.

Detailed Description

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Evaluation of postoperative prone position after major abdominal surgery. A randomized clinical trial of 100+100 patients and further add a voice/speech/singing protocol.

The patients will be randomized to the standard ERAS-protocol, enhanced recovery after surgery with or without adding periods of prone position after surgery.

They will be followed by protocol both as a momentum effect (experimental study) on POD 2-5 and also POD 7.

The aim is evaluation of prone position in order to improve the ventilation and hopefully diminish the risk of for example pneumonia and thromboembolism.

Inclusion criteria Patients referred to the Department of Surgery for major abdominal surgery of the esophagus, gastric- or pancreas surgery aim to cure.

Exclusion criteria Patients unable to understand Swedish in writing or speaking, preoperatively unable to perform a prone position.

The participation is voluntary and demands an inform consent from the patient operated upon.

The primary outcome is oxygen saturation and lung complications after surgery.

The secondary outcome is measurement of lung volumes, patient experience (7th graded Lickert scale), days of hospital care, 30 days complications etc.

Further investigations are perioperative properties as BMI, other forms of surgery, etc., and continues measurement of blood pressure, respiration frequency, heartrate, tubes and drainages, postoperative analgesic, blood samples with signs of bleeding, inflammation, infection.

Conditions

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Surgery Complications, Postoperative Lung Infection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

prospective randomized controlled study
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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ERAS

Ordinary ERAS treatment postoperatively without any prone position or voicetraining

Group Type NO_INTERVENTION

No interventions assigned to this group

+prone position

Ordinary ERAS treatment adding the prone position and voicetraining in short intervals

Group Type ACTIVE_COMPARATOR

prone position

Intervention Type PROCEDURE

Ordinary ERAS treatment postoperatvely adding the prone position and voicetraining

Interventions

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prone position

Ordinary ERAS treatment postoperatvely adding the prone position and voicetraining

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- malignancy of the esophagus, gastric- or pancreas

Exclusion Criteria

-.not able to understand Swedish in writing or speaking

\- preoperatively unable to perform a prone position
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vastra Gotaland Region

OTHER_GOV

Sponsor Role lead

Responsible Party

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Cecilia Engström-Mattisson

MD PhD Associated Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cecilia Engstrom Mattisson, MD PhD

Role: PRINCIPAL_INVESTIGATOR

Dept of Surgery, Sahlgrenska University Hospital, Gothenburg University, Sweden

Locations

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Dept of Surgery

Gothenburg, , Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Cecilia Engstrom Mattisson, MD PhD

Role: CONTACT

+46704970393

Cecilia Engstrom Mattisson, MD PhD

Role: CONTACT

Other Identifiers

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2021-06877-01

Identifier Type: -

Identifier Source: org_study_id

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