Prevention and Treatment of Perioperative Lung Injury in Elderly Patients

NCT ID: NCT05701449

Last Updated: 2023-01-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-31

Study Completion Date

2023-12-31

Brief Summary

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This study aims to verify the prediction model of postoperative pulmonary complications by collecting clinical information on elderly patients. In addition, the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model was compared.

Detailed Description

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More than 300 million major operations are performed worldwide each year, and older patients account for about a third of elective operations. Compared with young people, the elderly are more prone to postoperative complications due to age-related degeneration of the physiological functions of various organs and tissues. Postoperative pulmonary complications, including pneumonia, atelectasis, and respiratory failure, are common. Even mild pulmonary complications can lead to the prolonged hospital stay and increased postoperative mortality.

Although there have been many studies on postoperative lung complications, there have been few studies on elderly patients. In our country, the real incidence data of elderly patients after a perioperative period of pulmonary complications, the lack of effective prevention, intervention measures, and targeted prevention and treatment technology, these reasons lead to the clinical diagnosis and treatment of elderly patients after a perioperative period of pulmonary complications are very difficult. Therefore, the research team intends to verify the established prediction model of postoperative pulmonary complications and compare the incidence of postoperative pulmonary complications in elderly patients before and after using the prediction model.

Conditions

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Postoperative Pulmonary Complications Elderly Patients

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Patients applying a prediction model for postoperative pulmonary complications

No interventions assigned to this group

Patients non-applying a prediction model for postoperative pulmonary complications

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age 65 years or older
2. receiving invasive ventilation during general anesthesia for surgery

Exclusion Criteria

1. preoperative mechanical ventilation
2. procedures related to a previous surgical complication
3. a second operation after surgery within one week
4. organ transplantation
5. discharged within 24 hours after surgery
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China-Japan Friendship Hospital

OTHER

Sponsor Role collaborator

Taihe Hospital

OTHER

Sponsor Role collaborator

Chinese PLA General Hospital

OTHER

Sponsor Role collaborator

First Affiliated Hospital of Zhejiang University

OTHER

Sponsor Role collaborator

First Affiliated Hospital of Guangxi Medical University

OTHER

Sponsor Role collaborator

Qinghai People's Hospital

OTHER

Sponsor Role collaborator

Shanxi Cardiovascular Hospital

OTHER

Sponsor Role collaborator

Wuhan No.1 Hospital

OTHER

Sponsor Role collaborator

Shiyan City Renmin Hospital

OTHER_GOV

Sponsor Role collaborator

Dongfeng General Hospital of Chinese Medicine

UNKNOWN

Sponsor Role collaborator

Xiangyang Central Hospital

OTHER

Sponsor Role collaborator

Xiangyang No.1 People's Hospital

OTHER

Sponsor Role collaborator

Hubei University of Medicine

OTHER

Sponsor Role collaborator

Yunxi Renmin Hospital

UNKNOWN

Sponsor Role collaborator

Yunyang Renmin Hospital

UNKNOWN

Sponsor Role collaborator

Zhuxi Renmin Hospital

UNKNOWN

Sponsor Role collaborator

Danjiangkou First Hospital

UNKNOWN

Sponsor Role collaborator

Shiyan Integrated Traditional and Western Medicine Hospital

UNKNOWN

Sponsor Role collaborator

Shiyan Traditional Chinese Medicine Hospital

UNKNOWN

Sponsor Role collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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PPCS192023

Identifier Type: -

Identifier Source: org_study_id

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