An Observational Study to Assess Change in Disease Activity and Treatment Patterns of Upadacitinib When Given Alone or Co-Administered With Methotrexate in Adult Participants With Active Psoriatic Arthritis
NCT ID: NCT05616871
Last Updated: 2025-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
450 participants
OBSERVATIONAL
2022-12-15
2027-07-31
Brief Summary
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Upadacitinib (RINVOQ) is approved drug for the treatment of adult participants with active PsA in Europe. Approximately 450 adult participants who are prescribed Upadacitinib by their physician in accordance with local label will be enrolled in 4 countries in Europe: France, Germany, Greece and Italy.
Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 24 months.
There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Upadacitinib Alone or In Combination with Methotrexate
Participants will receive upadacitinib alone or in combination with methotrexate as prescribed by their physician according to local label in real- world practice.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Physician decision on participant treatment with upadacitinib must have been reached prior to and independently of recruitment in the study.
* Upadacitinib prescribed in accordance with the applicable approved label and local regulatory and reimbursement policies.
* Participants able to understand and communicate with the investigator and comply with the requirements of the study.
Exclusion Criteria
* Prior treatment with upadacitinib.
18 Years
ALL
No
Sponsors
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AbbVie
INDUSTRY
Responsible Party
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Principal Investigators
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ABBVIE INC.
Role: STUDY_DIRECTOR
AbbVie
Locations
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Centre Hospitalier Universitaire de Nice - Hôpital Pasteur /ID# 252536
Nice, Alpes-Maritimes, France
CH Troyes - Hopital Simone Veil /ID# 252625
Troyes, Aube, France
CHU de Besancon - Jean Minjoz /ID# 252537
Besançon, Doubs, France
CHU Limoges - Dupuytren 1 /ID# 252432
Limoges, Franche-Comte, France
CHU Toulouse - Hopital Purpan /ID# 252077
Toulouse, Haute-Garonne, France
CHU Montpellier - Hopital Saint Eloi /ID# 252078
Montpellier, Herault, France
CHU Grenoble - Hopital Michallon /ID# 252601
La Tronche, Isere, France
CHU Bordeaux - Hopital Pellegrin /ID# 252532
Bordeaux, Nouvelle-Aquitaine, France
Ch Beauvais /Id# 252464
Beauvais, Oise, France
Hopitaux Universitaires Henri Mondor - Hopital Henri Mondor /ID# 245194
Créteil, Paris, France
Infirmerie Protestante /ID# 252075
Caluire-et-Cuire, Rhone, France
CHU Amiens-Picardie Site Sud /ID# 252527
Amiens, Somme, France
Cabinet libéral du Dr PAUPIERE /ID# 252604
Péronne, Somme, France
Chic Castres-Mazamet /Id# 259557
Castres, Tarn, France
CH Henri Duffaut /ID# 252620
Avignon, Vaucluse, France
CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 259549
La Roche-sur-Yon, Vendee, France
CH AIX LES BAIN - Reine Hortense /ID# 252465
Aix-les-Bains, , France
Cabinet Médical Dr ALBERT-SABONNADIERE /ID# 252523
Antibes, , France
Centre Hospitalier d'Arras /ID# 252529
Arras, , France
Centre Hospitalier de Boulogne Sur Mer /ID# 252467
Boulogne-sur-Mer, , France
Centre Hospitalier Jean Rougie /ID# 259550
Cahors, , France
CH de Cannes - Simone Veil /ID# 252600
Cannes, , France
CHRU Tours - Hopital Trousseau /ID# 252528
Chambray-lès-Tours, , France
C. H. Sud Francilien /ID# 254945
Corbeil-Essonnes, , France
CH La Rochelle - Hopital Saint Louis /ID# 252534
La Rochelle, , France
Hopital St Joseph - St Luc (Lyon) /ID# 259561
Lyon, , France
Clinique de la Sauvegarde /ID# 252533
Lyon, , France
ELSAN - Clinique du Pont de Chaume /ID# 252602
Montauban, , France
CH de Narbonne /ID# 252525
Narbonne, , France
Centre Hospitalier Régional d'Orléans - Hôpital de la Source /ID# 252530
Orléans, , France
AP-HP - Groupe Hospitalier 10e - Hopital Lariboisiere /ID# 252526
Paris, , France
AP-HP - Hopital Saint-Antoine /ID# 252627
Paris, , France
AP-HP - Hopital Bichat - Claude-Bernard /ID# 252531
Paris, , France
GH Diaconesses Croix Saint-Simon /ID# 252463
Paris, , France
CHU de Rennes - Hospital Sud /ID# 252478
Rennes, , France
Hôpital Charles-Nicolle /ID# 252603
Rouen, , France
Cabinet Du Dr Judith Payet Dubourg /Id# 252668
Saint-Pierre-des-Corps, , France
Rheumazentrum Ruhrgebiet /ID# 252939
Herne, North Rhine-Westphalia, Germany
Beyer, Kaiserslautern, DE /ID# 254754
Kaiserslautern, Rhineland-Palatinate, Germany
Krankenhaus der Barmherzigen Brüder Trier /ID# 254762
Trier, Rhineland-Palatinate, Germany
Dr. Murawski /ID# 257911
Neunkirchen, Saarland, Germany
Rheumapraxis Dr. Prothmann /ID# 254759
Püttlingen, Saarland, Germany
Aurich & Sieburg, Magdeburg /ID# 255504
Magdeburg, Saxony-Anhalt, Germany
MVZ Ambulantes Rheumazentrum Erfurt /ID# 256115
Erfurt, Thuringia, Germany
Kupka & Kupka, Altenburg, DE /ID# 254758
Altenburg, , Germany
Rheumatologische Schwerpunktpraxis Brandt-Juergens /ID# 258152
Berlin, , Germany
Praxis Dr. Silke Zinke /ID# 258037
Berlin, , Germany
MVZ Herzogin Elisabeth Hospital /ID# 266740
Braunschweig, , Germany
Praxis Dilltal /ID# 254761
Ehringshausen, , Germany
Universitaetsmedizin Greifswald /ID# 254756
Greifswald, , Germany
Dr. Heintz /ID# 254757
Hamburg, , Germany
Dr. Bolze, Ludwigshafen, DE /ID# 254134
Ludwigshafen, , Germany
RHIO Forschungsinstitut /ID# 254752
Meerbusch, , Germany
Prof-med-stud.de /ID# 265965
Munich, , Germany
Knappschaftsklinikum Saar /ID# 255505
Püttlingen, , Germany
Krankenhaus St. Josef /ID# 254755
Wuppertal, , Germany
Olympion General Clinic /ID# 247644
Pátrai, Achaia, Greece
251 Airforce General Hospital /ID# 248092
Athens, Attica, Greece
Henry Dunnant Hospital Center /ID# 247640
Athens, Attica, Greece
General Hospital of Athens Gennimatas /ID# 247635
Athens, Attica, Greece
General Hospital of Athens Ippokratio /ID# 247633
Athens, Attica, Greece
General Hospital of Athens Laiko /ID# 247634
Athens, Attica, Greece
General Hospital of Athens Laiko /ID# 258030
Athens, Attica, Greece
University General Hospital Attikon /ID# 248093
Athens, Attica, Greece
General Hospital of Elefsina Thriassio /ID# 251900
Magoula (Attikis), Attica, Greece
Iaso /ID# 247649
Marousi, Attica, Greece
University General Hospital of Heraklion PA.G.N.I /ID# 247632
Heraklion, Crete, Greece
Naval Hospital of Athens /ID# 247631
Athens, , Greece
KAT Atttica General Hospital /ID# 247641
Athens, , Greece
University General Hospital of Ioannina /ID# 251899
Ioannina, , Greece
Iaso Thessalias S.A. /Id# 255110
Larissa, , Greece
Reg Gen Univ Hosp Larissa /ID# 247642
Larissa, , Greece
Bioclinic Thessaloniki /ID# 247648
Thessaloniki, , Greece
Euromedica Blue Cross Gen Clin /ID# 251898
Thessaloniki, , Greece
General Hospital of Thessaloniki Hippokrateio /ID# 247643
Thessaloniki, , Greece
Euromedica General Clinic /ID# 251897
Thessaloniki, , Greece
IRCCS Istituto Clinico Humanitas /ID# 251275
Rozzano, Lombardy, Italy
IRCCS Ospedale San Raffaele /ID# 251562
Milan, Milano, Italy
Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 251183
Naples, Napoli, Italy
Azienda Ospedaliera Universitaria Policlinico Tor Vergata /ID# 250817
Rome, Roma, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 250669
Rome, Roma, Italy
Azienda Ospedaliero Universitaria delle Marche /ID# 250819
Ancona, , Italy
A.O.U. Consorziale Policlinico di Bari /ID# 251508
Bari, , Italy
Universita degli Studi del Molise /ID# 251176
Campobasso, , Italy
Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone /ID# 250789
Palermo, , Italy
Fondazione IRCCS Policlinico San Matteo /ID# 250747
Pavia, , Italy
Azienda Ospedaliera Universitaria Senese /ID# 251146
Siena, , Italy
Azienda Ospedaliera Universitaria Friuli Centrale/Presidio Ospedaliero Universit /ID# 251544
Udine, , Italy
Countries
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Related Links
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Related info
Other Identifiers
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P22-897
Identifier Type: -
Identifier Source: org_study_id
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