A Study to Assess the Change in Disease State in Adult Participants Being Treated With Oral Upadacitinib Tablets in Participants With Oligo- or Poly-artIcular Psoriatic Arthritis
NCT ID: NCT04758117
Last Updated: 2024-07-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
394 participants
OBSERVATIONAL
2021-02-04
2023-07-26
Brief Summary
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Upadacitinib is a drug approved for the treatment of Psoriatic arthritis (PsA) in Germany and Canada. Approximately 380 adult participants with PsA at multiple sites in Germany and Canada.
Participants will receive oral Upadacitinib tablets per current local label, according to local standard of care and international guidelines.
There may be a higher burden for participants in this study compared to standard of care. Participants will attend regular visits per routine clinical practice. The effect of the treatment will be checked by medical assessments, checking for side effects, and by questionnaire.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Participants Receiving Upadacitinib
Participants receiving Upadacitinib for psoriatic arthritis (PsA).
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Swollen joint count (SJC) \>= 1 out of 66 joints.
* Decision on the treatment with Upadacitinib was made prior to any decision to approach the participant to participate in this study.
Exclusion Criteria
* Prior treatment with Upadacitinib.
* Currently participating in interventional research or within the last 30 days.
18 Years
ALL
No
Sponsors
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AbbVie
INDUSTRY
Responsible Party
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Principal Investigators
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ABBVIE INC.
Role: STUDY_DIRECTOR
AbbVie
Locations
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Dr. Jonathan D. Chan Inc. /ID# 241611
Vancouver, British Columbia, Canada
Manitoba Clinic /ID# 234148
Winnipeg, Manitoba, Canada
The Waterside Clinic /ID# 234146
Barrie, Ontario, Canada
Dr. Chrisostomos Kouroukis & Dr. Pauline Boulos MPC /ID# 233565
Dundas, Ontario, Canada
Arthur Karasik Medicine Professional Corporation /ID# 234147
Etobicoke, Ontario, Canada
Lau Bacchus Professional Medicine Corp /ID# 245283
Hamilton, Ontario, Canada
Credit Valley Rheumatology /ID# 234144
Mississauga, Ontario, Canada
Dr. L. Lisnevskaia Medicine Professional Corporation /ID# 239611
Oshawa, Ontario, Canada
Angela Montgomery Medicine Professional Corporation /ID# 239608
Ottawa, Ontario, Canada
Niagara Peninsula Arthritis Ct /ID# 245521
St. Catharines, Ontario, Canada
Dr. Sabeen Anwar Medicine Professional Corporation /ID# 242696
Windsor, Ontario, Canada
Applied Medical Informatics Research Inc. (AMIR) /ID# 239614
Montreal, Quebec, Canada
Clinique de Rhumatologie de Montreal /ID# 239613
Montreal, Quebec, Canada
CISSSBSL -Hopital regional de Rimouski /ID# 234150
Rimouski, Quebec, Canada
Groupe de Recherche en Maladies Osseuses Inc /ID# 234145
Sainte-Foy, Quebec, Canada
CIUSSS de l'Estrie - CHUS /ID# 241054
Sherbrooke, Quebec, Canada
Centre de Recherche Musculo-Squelettique /ID# 234151
Trois-Rivières, Quebec, Canada
Dr Naik-Medical Professional Corporation-Alliance Health /ID# 234149
Saskatoon, Saskatchewan, Canada
Praxis Dr. Rinaldi /ID# 228639
Ulm, Baden-Wurttemberg, Germany
Praxis Dres. Kellerer/Kellerer/Krüger /ID# 227414
Munich, Bavaria, Germany
Rheumahaus Studien GbR, Potsdam, DE /ID# 230771
Potsdam, Brandenburg, Germany
Internistisches Praxiszentrum /ID# 228262
Giessen, Hesse, Germany
Fachpraxis fuer Rheumatologie und Osteologie /ID# 227391
Bruchhausen-Vilsen, Lower Saxony, Germany
Kupka & Kupka, Altenburg, DE /ID# 228243
Altenburg, , Germany
Marycz, Amberg, DE /ID# 227413
Amberg, , Germany
Rheumapraxis am Webereck /ID# 229274
Augsburg, , Germany
MVZ Weserbergland /ID# 228806
Bad Pyrmont, , Germany
ACURA Rheumazentrum Baden-Bade /ID# 239202
Baden-Baden, , Germany
Rheumapraxis Prof Dr Karin Manger /ID# 229120
Bamberg, , Germany
Sozialstiftung Bamberg /ID# 228549
Bamberg, , Germany
Internistische-rheumatologische Praxisgemeinschaft /ID# 228240
Bayreuth, , Germany
MVZ Rheumatologie /ID# 240868
Berlin, , Germany
Praxis Dr. med. Angela Seifert /ID# 233772
Berlin, , Germany
Praxis Dr. Silke Zinke /ID# 229127
Berlin, , Germany
Rheumapraxis am Schlachtensee /ID# 228800
Berlin, , Germany
Eisterhues, Braunschweig, DE /ID# 227390
Braunschweig, , Germany
Dres. Schuh /ID# 227411
Coburg, , Germany
Rheumatologie in Veedel /ID# 228469
Cologne, , Germany
Krankenhaus Porz am Rhein /ID# 228358
Cologne, , Germany
Praxis Dr. Kirrstetter /ID# 229609
Deggendorf, , Germany
Kreiskrankenhaus Demmin /ID# 228253
Demmin, , Germany
Rheumatologisches MVZ Dresden /ID# 230787
Dresden, , Germany
Praxis Dilltal /ID# 228640
Ehringshausen, , Germany
MVZ Ambulantes Rheumazentrum Erfurt /ID# 248933
Erfurt, , Germany
Dres. Waehrisch/Flaxenberg /ID# 228263
Essen, , Germany
Michael Mueller, Freiberg, DE /ID# 228468
Freiberg, , Germany
Praxis Dr. Behringer /ID# 229275
Fulda, , Germany
Rockwitz, Goslar, DE /ID# 227856
Goslar, , Germany
Praxis Fiene /ID# 244732
Greifswald, , Germany
Praxis Dr. Kuehne /ID# 229119
Haldensleben I, , Germany
Praxis Dr. Liebhaber /ID# 228636
Halle, , Germany
Stille, Hanover, DE /ID# 229604
Hanover, , Germany
Heilig, Heidelberg, DE /ID# 228356
Heidelberg, , Germany
St. Elisabeth Gruppe GmbH -Katholische Kliniken /ID# 228797
Herne, , Germany
Praxis Bernd Mueller /ID# 230776
Homburg, , Germany
Praxis K. Pagel /ID# 228247
Hoppegarten, , Germany
Kremers, Juelich, DE /ID# 240383
Jülich, , Germany
Rheumapraxis Kaufering /ID# 231391
Kaufering, , Germany
Alb-Donau Klinikum, Langenau /ID# 233770
Langenau, , Germany
Hamann & Teich & Boche,Leipzig /ID# 228355
Leipzig, , Germany
Praxis internistische Rheumatologie /ID# 227857
Leipzig, , Germany
Dres. Teipel/Toussaint/Saech /ID# 228465
Leverkusen, , Germany
Dr. Bolze, Ludwigshafen, DE /ID# 230773
Ludwigshafen, , Germany
Aurich & Sieburg, Magdeburg /ID# 229605
Magdeburg, , Germany
Praxis Dr. Annekatrin Rossbach /ID# 230783
Mansfeld / Großörner, , Germany
Harmuth, Marktredwitz, DE /ID# 227709
Marktredwitz, , Germany
RHIO Forschungsinstitut /ID# 227736
Meerbusch, , Germany
Vollmer & Partner, DE /ID# 240869
Mönchengladbach, , Germany
Prof-med-stud.de /ID# 228637
Munich, , Germany
Rheumatologische Facharztpraxis /ID# 228808
Naumburg, , Germany
Berger, Naunhof, DE /ID# 229612
Naunhof, , Germany
Praxis Dr. med Thilo Klopsch /ID# 229123
Neubrandenburg, , Germany
Erbsloeh-Moeller, Neunkirchen /ID# 230778
Neunkirchen, , Germany
MVZ Medic-Center Nürnberg GmbH /ID# 240982
Nuremberg, , Germany
Die Fachaerzte im Rottal - Nephrologie, Rheumatologie /ID# 230774
Pfarrkirchen, , Germany
MVZ für Rheumatologie Dr. M. Welcker /ID# 227858
Planegg, , Germany
Baumann & Lang, Plauen, DE /ID# 229128
Plauen, , Germany
Praxis Dr. Sabine Reckert /ID# 248986
Potsdam, , Germany
Knappschaftsklinikum Saar /ID# 248882
Püttlingen, , Germany
Rheumazentrum Ratingen /ID# 228261
Ratingen, , Germany
Rheumatologische Praxis Dr. Jochen Walter /ID# 229607
Rendsburg, , Germany
Rheumatologische Gemeinschaftspraxis Schwerin /ID# 228260
Schwerin, , Germany
Melzer, Seesen, DE /ID# 227386
Seesen, , Germany
Barmherzige Bruder MVZ Klinikum Straubing GmbH /ID# 228805
Straubing, , Germany
Krankenhaus der Barmherzigen Brueder Trier /ID# 229603
Trier, , Germany
Praxis Dr. Haas /ID# 228813
Tübingen, , Germany
Rheumathologie Ulm /ID# 238801
Ulm, , Germany
MVZ Lahn-Dill-Kliniken GmbH /ID# 231390
Wetzlar, , Germany
MVZ Lahn-Dill-Kliniken GmbH /ID# 262011
Wetzlar, , Germany
Krankenhaus St. Josef /ID# 229611
Wuppertal, , Germany
Praxis Barmen /ID# 227392
Wuppertal, , Germany
Sprekeler, Zeven, DE /ID# 233773
Zeven, , Germany
Fricke-Wagner, Zwickau, DE /ID# 230775
Zwickau, , Germany
Countries
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References
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Werner SG, Baraliakos X, Reckert S, Bohl-Buhler M, Laliberte MC, Girard T, Jeromin K, Baschuk N, Fritz B, Bessette L, Hueber AJ. Treatment with Upadacitinib in Active Psoriatic Arthritis: Efficacy and Safety Data of the First 192 Patients from the UPJOINT Study, a Multicentre, Observational Study in Clinical Practice. Rheumatol Ther. 2023 Dec;10(6):1503-1518. doi: 10.1007/s40744-023-00589-3. Epub 2023 Sep 11.
Related Links
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clinical study report synopsis
Other Identifiers
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P20-483
Identifier Type: -
Identifier Source: org_study_id
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