Retrospective Study on the Evolution of CIN 1 to 3 in Per and Postpartum in Nancy From 2014 to 2022

NCT ID: NCT05595252

Last Updated: 2022-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2022-12-31

Brief Summary

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In France, the screening rate for cervical cancer remains too low. Screening is simple and non-invasive.

Pregnant patients are most of the time young and are part of the target population for screening, and for many women, it is the first encounter with a gynecologist.

The cervical smear is therefore an important step of the first consultation during pregnancy In the case of pathological results, colposcopies with biopsies are performed, frequently finding CIN 1 to 3. (cervical intraepithelial neoplasia) These CIN lesions evolve slowly and most of the time, treatment can be withheld until the end of the pregnancy.

Several studies suggest a higher regression rate in pregnant patients. Our study will evaluate the rate of regression, progression or persistence of these lesions in per and post partum patients in Nancy, between 2014 and 2022.

To obtain our results, we will compare the results of per and post partum biopsies in each patient.

In a second step, we will study the risk factors of aggravation or on the contrary the protective factors, allowing a faster regression of the lesions

Detailed Description

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Conditions

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Cervical Intraepithelial Neoplasia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with CIN lésions during pregnancy

cervical biopsy

Intervention Type BIOLOGICAL

cervical biopsy made during and after pregancy

Interventions

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cervical biopsy

cervical biopsy made during and after pregancy

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* women who have a CIN lesion during pregnancy
* in Nancy, France, MRUN Center
* between 2014 and 2022

Exclusion Criteria

* lost of follow up women
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Central Hospital, Nancy, France

OTHER

Sponsor Role lead

Responsible Party

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MARTIN Elena

Assistant clinical Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Camille BENOIT

Role: PRINCIPAL_INVESTIGATOR

CHRU Nancy

Locations

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BENOIT Camille

Nancy, , France

Site Status

Countries

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France

Other Identifiers

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2022PI157/EUDRACT

Identifier Type: -

Identifier Source: org_study_id

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