Neural Bases of Post-stroke Emotion Perception Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-16

Study Completion Date

2025-10-31

Brief Summary

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This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs. healthy controls using MRI (functional and structural connectivity) and EEG.

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Detailed Description

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This monocentric physiological study will evaluate the neural bases of visual recognition of emotions in stroke patients vs healthy controls (2 groups of 40 subjects). It will include functional MRI, structural MRI (disconnectome), EEG, and behavioral assessments of emotion recognition and executive functions.

Conditions

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Stroke Stroke Sequelae Emotions

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Stroke

Stroke patients (ischemic or hemorrhagic) in the chronic phase (\> 6 months)

No interventions assigned to this group

Healthy controls

Healthy adult controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

Stroke group:

* Man or Woman
* Age 18-80y
* Unique stroke, ischemic or hemorrhagic
* at the chronic phase (\< 6 months)
* Written informed consent
* subject having a social insurance
* Subject who consent to complete all the study's experiments

Healthy controls group:

* Man or Woman
* Age 18-80y
* No history of neurological or psychiatric disease.

Exclusion Criteria

Stroke group

* Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
* History of other neurologic disorders
* Significant le vel of depression or anxiety, assessed by the STAI and the BDI questionnaires
* Non corrected visual loss
* Subjects suffering from visual neglect (assessed by the Bells Test and a bisection test (20mm)
* contra-indications to MRI
* pregnant or breastfeeding woman
* Women of childbearing age without effective contraception

Healthy controls group

* Subject who is unable to consent (due to dementia, severe aphasia, psychiatric disorder...)
* History of neurologic disorders
* Significant level of depression or anxiety, assessed by the STAI and the BDI questionnaires
* Non-corrected visual loss
* contra-indications to MRI
* pregnant or breastfeeding woman
* Women of childbearing age without effective contraception

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes