Platelet Rich Fibrin Versus Melatonin Around Dental Implants

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-10

Study Completion Date

2022-08-10

Brief Summary

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Dental implant is a dental treatment that allow oral rehabilitation for partial and fully edentulous patients. Osteointegration is the factor that control success s or failure of dental implant that can be improved by addition of different adjunctive biological materials. Platelets Rich fibrin plays a significant role in tissue regeneration and wound healing. Melatonin is biological hormone that secreted from pineal gland and played an important role in human growth.

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Detailed Description

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Conditions

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Patients With Missing Teeth

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Investigators

Study Groups

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dental implants alone

Group Type OTHER

dental implants with melatonin gel

Intervention Type BIOLOGICAL

platelet rich fibrin membrane around dental implants

platelet rich fibrin

dental implants with platelet rich fibrin membrane

Group Type ACTIVE_COMPARATOR

dental implants with melatonin gel

Intervention Type BIOLOGICAL

platelet rich fibrin membrane around dental implants

melatonin gel

dental implants with melatonin gel around dental implants

Group Type ACTIVE_COMPARATOR

dental implants with melatonin gel

Intervention Type BIOLOGICAL

platelet rich fibrin membrane around dental implants

Interventions

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dental implants with melatonin gel

platelet rich fibrin membrane around dental implants

Intervention Type BIOLOGICAL

Other Intervention Names

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dental implants with platelet rich fibrin

Eligibility Criteria

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Inclusion Criteria

1. good oral hygiene participants,
2. free of any systemic diseases,
3. Patients' age ranged from 20 to 40 years old.
4. Patients who can complete surgery and the study protocol.
5. Partially edentulous patients in the posterior mandibular region (at least a single-mandibular edentulous area) with periodontal health.

Exclusion Criteria

1. patients who had parafunctional habits,
2. current and former smokers, pregnant
3. lactating women
4. unmotivated patients
5. patients with psychological problems
6. patients who were not able to follow the treatment protocol -

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes