3 Snip Punctoplasty With and Without Mitomycine C.

NCT ID: NCT05586620

Last Updated: 2022-10-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-01

Study Completion Date

2022-06-10

Brief Summary

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Punctal stenosis is a progressive constriction of the puncta with resultant epiphora. One of the most effective treatment options is 1- to 4-snip punctoplasty combined with or without Mitomycin-C.

Detailed Description

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Conditions

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Punctal Stenosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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3-snip punctoplasty

Group Type ACTIVE_COMPARATOR

3-snip punctoplasty

Intervention Type PROCEDURE

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease.

3-snip punctoplasty with mitomycin C

Group Type ACTIVE_COMPARATOR

3-snip punctoplasty and Mitomycin C

Intervention Type PROCEDURE

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease.

Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis

Interventions

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3-snip punctoplasty

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease.

Intervention Type PROCEDURE

3-snip punctoplasty and Mitomycin C

punctoplasty, more commonly known as watery eye surgery, is an ophthalmic surgical procedure performed to correct punctal stenosis (a condition that causes tears to overflow from the eyes) by widening the punctal opening to allow the tears to drain with ease.

Mitomycin C is a chemotherapeutic agent that acts by inhibiting DNA synthesis

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with recurrence of punctal stenosis at the end of 1 month following punctal dilatation.

Exclusion Criteria

* patients with associated lacrimal passage obstruction
Minimum Eligible Age

16 Years

Maximum Eligible Age

63 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Ehab tharwat

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ehab tharwat

Damietta, New Damietta, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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3 Snip Punctoplasty

Identifier Type: -

Identifier Source: org_study_id

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