Evaluation of the Diagnostic Performance of a Bra Prototype to Detect Breast Cancer

NCT ID: NCT05574816

Last Updated: 2024-06-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-30

Study Completion Date

2024-02-01

Brief Summary

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Phi-Bra is a prospective and monocentric pilot study to assess the diagnostic capability of an innovative bra prototype to detect breast cancer, compared to the current standard of care: the mammography.

The Phi-Bra prototype is designed with sensors measuring different parameters simultaneously such as impedance and temperature.

The bra will be tested on patients without breast lump (American College of Radiology (ACR) 1 et 2 Birads classification) and with breast lump (ACR 4b, c ou ACR 5 Birads classification).

The aim of this pilot study is to compare the results obtained by Phi-Bra to the ones obtained by mammography.

The Phi-Bra study is classified as clinical investigation category 4.4 based on the European Union (EU) regulation (DM 2017/745).

Detailed Description

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Conditions

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Breast Neoplasm Female

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Patient without breast lump

No breast lump identified during mammography (ACR 1 et 2 Birads classification)

Group Type ACTIVE_COMPARATOR

Phi-Bra prototype measurements

Intervention Type DEVICE

The bra prototype will be placed on the patient's breast. The patient will stay in a half-lying position during 15 min, the time duration of the measurements. Measurements will not be painful.

Measurements will only be realized one time during the first and unique visit of the patient.

Patient with breast lump

Suspicious breast lump identified during mammography (ACR 4b, c ou ACR 5 Birads classification)

Group Type EXPERIMENTAL

Phi-Bra prototype measurements

Intervention Type DEVICE

The bra prototype will be placed on the patient's breast. The patient will stay in a half-lying position during 15 min, the time duration of the measurements. Measurements will not be painful.

Measurements will only be realized one time during the first and unique visit of the patient.

Interventions

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Phi-Bra prototype measurements

The bra prototype will be placed on the patient's breast. The patient will stay in a half-lying position during 15 min, the time duration of the measurements. Measurements will not be painful.

Measurements will only be realized one time during the first and unique visit of the patient.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 75.
* No breast cancer surgery background
* Bra size : S/M or M/L

Specific criteria for the "no breast lump" cohort:

\- Negative mammography result (ACR 1 a 2).

Specific criteria for the "breast lump" cohort:

\- Suspicious breast lump discovered during the mammography (ACR 4b ou c ou ACR 5) and for which there is an indication of microbiopsy.

Exclusion Criteria

* Breast cancer background (surgery or radiotherapy)
* Breast lump classified as ACR 3 ou ACR 4a during the mammography
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marion CORTET, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Hospices Civils de Lyon

Locations

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Service de Gynecologie-Obstetrique, Hopital de la Croix Rousse

Lyon, , France

Site Status

Service de Radiologie, Hôpital de la Croix-Rousse

Lyon, , France

Site Status

Countries

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France

Other Identifiers

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69HCL21_1085

Identifier Type: -

Identifier Source: org_study_id

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