Treatment of Moderate FMR During AVR

NCT ID: NCT05566340

Last Updated: 2022-10-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

154 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-10-31

Study Completion Date

2023-12-31

Brief Summary

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Debates exist on the treatment of moderate functional mitral regurgitation (FMR) in patients undergoing aortic valve replacement (AVR) for aortic valve disease. This study aims to evaluate the left ventricular function, which was evaluated through global longitudinal strain, after isolated AVR and AVR + mitral valve repair (MVr) in this group of patients.

Detailed Description

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Conditions

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Functional Mitral Regurgitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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isolated aortic valve replacement group

Isolated aortic valve replacement surgery.

mitral valve repair

Intervention Type PROCEDURE

Repair of mitral valve concomitant to aortic valve replacement.

aortic valve replacement with mitral valve repair group

Aortic valve replacement with mitral valve repair

mitral valve repair

Intervention Type PROCEDURE

Repair of mitral valve concomitant to aortic valve replacement.

Interventions

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mitral valve repair

Repair of mitral valve concomitant to aortic valve replacement.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Patients who received AVR (with or without concomitant MVr) from two center (Fuwai Yunnan Cardiovascular Hospital and Fuwai Hospital, Chinese Academy of Medical Sciences).
2. Age more than 18 years.

Exclusion Criteria

1. Those with a history of rheumatic valvular disease or infective endocarditis.
2. Primary mitral valve lesions.
3. Patients receiving mitral valve replacement.
4. Patient who refuse to participate in this study, or cannot complete 6-month follow-up after surgery.
5. Age \< 18 years.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fuwai Yunnan Cardiovascular Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Xieraili Tiemuerniyazi

Role: CONTACT

+86-18814115887

Other Identifiers

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FZX2019-06-01 2022YFKY088

Identifier Type: -

Identifier Source: org_study_id

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