Invasive Hemodynamic Response to Transcatheter Edge-to-Edge Mitral Valve Repair

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

22 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-20

Study Completion Date

2024-04-11

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Studying the effects of Trans-catheter Mitral Valve Repair (TMVr) on the hemodynamics and biomarkers in patients with severe mitral valve regurgitation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock

NCT05298124

Cardiogenic Shock Mitral Regurgitation

RECRUITING NA

Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair

NCT04913727

Severe Mitral Regurgitation

RECRUITING NA

Transcatheter Versus Standard Surgical Mitral Valve Operation for Secondary Mitral Regurgitation

NCT05090540

Severe Mitral Valve Regurgitation (Disorder)

ENROLLING_BY_INVITATION

Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry

NCT05332782

Mitral Regurgitation

RECRUITING

Early Transcatheter Mitral Valve Repair After Myocardial Infarction

NCT06282042

Acute Mitral Regurgitation

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mitral Regurgitation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Subjects undergoing TMVr

Subjects with severe, symptomatic primary mitral regurgitation (MR) scheduled to undergo a transcatheter mitral valve repair (TMVr) as standard of care will have intra-op baseline and post repair blood draws. Pre-procedure and post-procedure transthoracic echocardiograms (TTE) will assess the hemodynamic implications of the repair.

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Adults (age ≥ 18 years) with severe, symptomatic primary mitral regurgitation identified by Doppler transthoracic echocardiogram
* Heart team (cardiologist and cardiac surgeon) agree that patient would be eligible for TMVR with Transcatheter edge to edge repair device.
* TMVR procedure will be performed in the cardiac catheterization laboratory for hemodynamic data recording