Measuring the Impact of an Enhanced Strategy for Daily Disinfection in Acute Care Hospital Rooms
NCT ID: NCT05560321
Last Updated: 2022-09-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2019-08-22
2022-03-17
Brief Summary
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Detailed Description
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This trial was conducted in acute care hospital rooms at Duke University Hospital in Durham, North Carolina from November 2021 to March 2022. Room surfaces were divided in two (e.g., right vs. left), allowing each patient room to serve as its own control. The intervention was a quaternary ammonium salt-based 24-hour continuously active germicidal wipe, Sani-24 (PDI Healthcare, Woodcliff, NJ) that was applied in addition to routine disinfection. The control arm received no intervention beyond routine disinfection. Environmental services were blinded to study arms and no changes to routine cleaning protocols occurred during the study period. Room contamination was measured immediately before the application of the disinfectant (study day 0) and 24-hours later (day 1). Secondary outcomes included evaluation for clinically important pathogens (CIP), including methicillin-resistant staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE) and carbapenem-resistant Enterobacteriaceae (CRE)
Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
QUADRUPLE
Study Groups
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Intervention
Application of a 24-hour continuously acting quaternary ammonium salt disinfectant: Sani24 (PDI Healthcare Inc.) by study team
Sani24
Disinfectant
Routine Disinfection
Routine disinfection at the study hospital
Control
Routine disinfection completed by hospital staff
Routine Disinfection
Routine disinfection at the study hospital
Interventions
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Sani24
Disinfectant
Routine Disinfection
Routine disinfection at the study hospital
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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PDI Healthcare Inc.
UNKNOWN
Duke University
OTHER
Responsible Party
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Principal Investigators
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Nick Turner, MD
Role: PRINCIPAL_INVESTIGATOR
Duke School of Medicine
Locations
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Duke University
Durham, North Carolina, United States
Countries
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References
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Warren BG, Barrett A, Graves A, King C, Turner NA, Anderson DJ. An Enhanced Strategy for Daily Disinfection in Acute Care Hospital Rooms: A Randomized Clinical Trial. JAMA Netw Open. 2022 Nov 1;5(11):e2242131. doi: 10.1001/jamanetworkopen.2022.42131.
Other Identifiers
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Pro00103576
Identifier Type: -
Identifier Source: org_study_id
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