Effect of Sumac on Appetite and Food Intake

NCT ID: NCT05534152

Last Updated: 2023-09-06

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-11-01
• Study Completion Date: 2020-03-15

Brief Summary

Sumac, is a spice that is widely used in Turkish, Iranian and Middle Eastern foods. In these regions, the fruit of sumac is used for seasoning or flavouring, as an appetizer and for souring food. This spice has also been used in herbal folk medicine to relieve certain conditions including bowel disorders, anorexia and indigestion. In addition, many studies have shown that sumac contains a high level of antioxidant activity and polyphenol content that may benefit certain diseases such as cancer and diabetes. The aim of this study was to assess the level of the appetite and food intake among young adults in comparison with free living older adults following the consumption of sumac. This was achieved by assessing the amount of food intake during a lunch course and the impact on food intake for the subsequent 12 hours.

Detailed Description

Rhus coriaria Linn, also known as Sumac, is a spice that is widely used in Turkish, Iranian and Middle Eastern foods. In these regions, the fruit of sumac is used for seasoning or flavouring, as an appetizer and for souring food. This spice has also been used in herbal folk medicine to relieve certain conditions including bowel disorders, anorexia and indigestion. In addition, many studies have shown that sumac contains a high level of antioxidant activity and polyphenol content that may benefit certain diseases such as cancer and diabetes.

Taste and smell perception may play a vital role in food preference, nutrient intake and appetite; however, both ageing and disease can have a negative impact on these senses. It has been suggested that by 2025 the older adult population (i.e. those aged 60years and over) worldwide will rapidly increase and reach 1.12 billion. One of the major physiological changes in this age group is the loss or reduction in sensory perception including smell and taste. These changes as a result of ageing and medication increase the risk of poor health by reducing the enjoyment of food followed by decreasing food and nutrient intake.

It is possible, therefore, that all these factors together may lessen the enjoyment of food, leading to malnutrition and disease complications. In light of the above, the aim of this study was to assess the level of the appetite and food intake among young adults in comparison with free living older adults following the consumption of sumac. This was achieved by assessing the amount of food intake during a lunch course and the impact on food intake for the subsequent 12 hours.

This study assessed the use of sumac at 1% dose (0.37g) of total volume of a vegetable soup (150g), in two forms: 1) added to finished cooked soup 2) added to the soup from the beginning of the cooking process, in addition to consumption of the same soup without added sumac as the control soup. The study comprised of 20 young adults (18-35 years old) and 20 free living older adults aged >65 years. Each participant in these groups attended the Oxford Brookes Centre for Nutrition and Health (OxBCNH) for three sessions and each session lasted up to one hour.

Conditions

Appetite; Food Intake

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: SINGLE

Study Groups

Soup with no sumac

150 g butternut squash soup with no added sumac

Group Type: PLACEBO_COMPARATOR

sumac

Intervention Type: OTHER

1% iranian brown sumac

Sumac added to soup at the end of cooking

150 g butternut squash soup with 1% sumac added at the end of cooking

Group Type: EXPERIMENTAL

sumac

Intervention Type: OTHER

1% iranian brown sumac

Sumac added to the sumac during cooking

150 g butternut squash soup with 1% sumac added during cooking

Group Type: EXPERIMENTAL

sumac

Intervention Type: OTHER

1% iranian brown sumac

Interventions

sumac

1% iranian brown sumac

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• • Adults, aged >65 years

• Adults, 18-35 years
• No allergy to any herbs and spices
• No allergy to vegetables including celery and tomato
• Non-smoker
• Do not have a cold or hay fever (on test day)
• No medication that may affect the sensory taste such as: antibiotics, antihistamines and decongestants, anti-inflammatory agents, and muscle relaxants (Bromley, 2000)
• Ability to read and understand written information in English
• Ability to attend, stand and sit for up to one hour
• The normal level of capability of functional activity (i.e. traveling out to the neighbourhood, shopping alone)
• Not diagnosed with Dementia

Exclusion Criteria

• Disease that may affect the taste and smell sensation including local chronic or acute inflammatory nasal disease and oral and perioral infections

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Oxford Brookes University

OTHER

Sponsor Role: lead

Responsible Party

Dr. Sangeetha Thondre

Senior Lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Sangeetha Thondre, PhD

Role: PRINCIPAL_INVESTIGATOR

Oxford Brookes University

Locations

Oxford Brookes Centre for Nutrition and Health

Oxford, , United Kingdom

Countries

United Kingdom

Other Identifiers

UREC 181174

Identifier Type: -

Identifier Source: org_study_id