Ultrasound-guided Continuous Low Serratus Anterior Plane Block in Hepatocellular Carcinoma Surgery

NCT ID: NCT05531864

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-01

Study Completion Date

2024-02-29

Brief Summary

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To investigate the clinical application of ultrasound-guided continuous low serratus anterior plane block in open surgery for hepatocellular carcinoma.

Detailed Description

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METHODS: Patients with hepatocellular carcinoma who attended our hospital from January 2021 to April 2023 were divided into CS group and N group according to the random number table method; CS group underwent ultrasound-guided continuous low anterior serratus plane block and N group underwent ultrasound-guided single anterior serratus plane block combined with rectus abdominis sheath block; the operation time, anesthesia time, incision length, sensory block time and sensory block maintenance time were counted and recorded. Pain score (NRS) was used to detect analgesia; alanine aminotransferase (ALT), liver function aspartate aminotransferase (AST), and prothrombin time (The time of thrombin, NRS) were measured by fluorescent quantitative PCR. (The time of thrombin (APTT), total bilirubin (TBIL) levels and adverse reactions.

Conditions

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Liver Neoplasms Postoperative Analgesia Serratus Anterior Plane Block

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Continuous serratus anterior plane block

Ultrasound-guided continuous serratus anterior plane block.

Group Type EXPERIMENTAL

Ultrasound-guided continuous low serratus anterior plane block

Intervention Type PROCEDURE

Low anterior serratus plane block, move the mid-axillary line 4 and 5 intercostal puncture points are moved down and the puncture is changed to 7 and 8 intercostal.

Single serratus anterior plane block combined with rectus sheath nerve block

Ultrasound-guided single serratus anterior plane block combined with rectus sheath nerve block.

Group Type ACTIVE_COMPARATOR

Ultrasound-guided single serratus anterior plane block

Intervention Type PROCEDURE

Ultrasound-guided single anterior saw plane block was performed, and a needle was injected between the 4th and 5th costals in the midaxillary line.

Interventions

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Ultrasound-guided continuous low serratus anterior plane block

Low anterior serratus plane block, move the mid-axillary line 4 and 5 intercostal puncture points are moved down and the puncture is changed to 7 and 8 intercostal.

Intervention Type PROCEDURE

Ultrasound-guided single serratus anterior plane block

Ultrasound-guided single anterior saw plane block was performed, and a needle was injected between the 4th and 5th costals in the midaxillary line.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Age 18-60 years;
2. ASAI-II;
3. BMI: 18-29 kg/m2

Exclusion Criteria

1. Combined cardiac, cerebral, hepatic, and renal failure;
2. Comorbid psychiatric and neuromuscular disorders;
3. A history of allergy to anesthetic drugs;
4. Participation in other recent clinical or drug trials.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Liu Di

OTHER

Sponsor Role lead

Responsible Party

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Liu Di

Principal Investigator

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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ailing wu, Doctor

Role: STUDY_DIRECTOR

First People's Hospital of Neijiang.

Locations

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The First People's Hospital of Neijiang

Neijiang, Sichuan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jiang Fei

Role: CONTACT

18283236053 ext. 1

Facility Contacts

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Hengchun Shen, master

Role: primary

15599237557

Other Identifiers

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JF20PJ288

Identifier Type: -

Identifier Source: org_study_id

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