International Ledless Pacemaker Registry

NCT ID: NCT05528029

Last Updated: 2022-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-09-01

Study Completion Date

2024-12-31

Brief Summary

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The Micra MC1VR01 or Micra AVMC1AVR1 Transcatheter Pacing System (Medtronic, Inc., Minneapolis, MN, USA) has become a major breakthrough as an alternative to standard transvenous pacemakers.

The aim of this multi-center study is to assess the clinical outcomes of patients implanted with Micra LLPM in real life, in different clinical scenarios.

Detailed Description

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The study includes consecutive patients implanted with a pacemaker leadless device (Micra Transcatheter Pacing System; Medtronic, Inc., Minneapolis, MN, USA).

Baselines characteristics, procedural and clinical outcomes will be collected and analyzed.

Conditions

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Block Complete Heart Atrial Fibrillation

Keywords

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leadless pacing

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Leadless Pacemaker (Micra)

Micra leadless pacemaker is implanted in the right ventricle via femoral vein. The Micra introducer/dilator assembled system is inserted over a stiff guidewire in the right atrium. After the removal of the guidewire and the dilator, the delivery system is advanced into the introducer and the Micra is placed under fluoroscopy guidance, preferably in the septal region of the right ventricle.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* At least 1 month of follow up
* At least 1 post-implantation assessment, in accordance to the routine clinical practice of every center

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Università degli Studi di Brescia

OTHER

Sponsor Role collaborator

Centro Cardiologico Monzino

OTHER

Sponsor Role collaborator

University Hospital, Zürich

OTHER

Sponsor Role collaborator

Azienda Ospedaliera Cardinale G. Panico

OTHER

Sponsor Role collaborator

Azienda Ospedaliera San Gerardo di Monza

OTHER

Sponsor Role collaborator

IRCCS Azienda Ospedaliero-Universitaria di Bologna

OTHER

Sponsor Role collaborator

San Raffaele University Hospital, Italy

OTHER

Sponsor Role collaborator

Ospedale V. Fazzi

OTHER

Sponsor Role collaborator

Ospedali Riuniti Ancona

OTHER

Sponsor Role collaborator

Universitair Ziekenhuis Brussel

OTHER

Sponsor Role collaborator

Università degli Studi di Ferrara

OTHER

Sponsor Role collaborator

University of Padova

OTHER

Sponsor Role collaborator

Luigi Sacco University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Giovanni B Forleo

Section Head Electrophysiology and Clinical Pacing

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Giovanni B Forleo, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Luigi Sacco University Hospital

Gianfranco MItacchione, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Luigi Sacco University Hospital

Locations

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Heart Rhythm Management Centre, Universitair Ziekenhuis Brussel, Postgraduate program in Cardiac Electrophysiology and Pacing, European Reference Networks Guard-Heart, Vrije Universiteit

Brussels, , Belgium

Site Status RECRUITING

Cardiology and Arrhythmology Clinic, University Hospital "Umberto I-Salesi-Lancisi", Ancona (IT)

Ancona, , Italy

Site Status RECRUITING

Department of Cardiology, IRCCS, Azienda Ospedaliero Universitaria Di Bologna, Policlinico Di S. Orsola

Bologna, , Italy

Site Status RECRUITING

Spedali Civili di Brescia

Brescia, , Italy

Site Status RECRUITING

Cardiology Unit, Vito Fazzi Hospital, Lecce (IT)

Lecce, , Italy

Site Status RECRUITING

Arrhythmology and Electrophysiology Unit, San Raffaele Hospital, IRCCS

Milan, , Italy

Site Status RECRUITING

Azienda Ospedaliera - Polo Universitario - "Luigi Sacco"

Milan, , Italy

Site Status RECRUITING

Department of Clinical Electrophysiology and Cardiac Pacing, Centro Cardiologico Monzino, IRCSS

Milan, , Italy

Site Status RECRUITING

Department of Cardiology, ASST Monza, San Gerardo Hospital

Monza, , Italy

Site Status RECRUITING

Departtment of Cardiac, Thoracic Vascular Sciences and Public Health University of Padova

Padua, , Italy

Site Status RECRUITING

Cardiology Unit, "Card. G. Panico" Hospital, Tricase (IT)

Tricase, , Italy

Site Status RECRUITING

University Hospital Zurich,

Zurich, , Switzerland

Site Status RECRUITING

Countries

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Belgium Italy Switzerland

Central Contacts

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Giovanni B Forleo, MD, PhD

Role: CONTACT

Phone: 390239042789

Email: [email protected]

Marco Schiavone, MD

Role: CONTACT

Phone: +390239042789

Email: [email protected]

Facility Contacts

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Carlo De Asmundis, MD

Role: primary

Antonio Dello Russo, MD, PhD

Role: primary

Mauro Biffi, MD

Role: primary

Antonio Curnis, MD

Role: primary

Ennio Pisanò, MD

Role: primary

Simone Gulletta, MD

Role: primary

Giovanni Battista Forleo, MD, PhD

Role: primary

Claudio Tondo, MD, PhD

Role: primary

Giovanni Rovaris, MD

Role: primary

Federico Migliore, MD

Role: primary

Pietro Palmisano, MD

Role: primary

Ardan M Sagunder, MD

Role: primary

References

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Reynolds D, Duray GZ, Omar R, Soejima K, Neuzil P, Zhang S, Narasimhan C, Steinwender C, Brugada J, Lloyd M, Roberts PR, Sagi V, Hummel J, Bongiorni MG, Knops RE, Ellis CR, Gornick CC, Bernabei MA, Laager V, Stromberg K, Williams ER, Hudnall JH, Ritter P; Micra Transcatheter Pacing Study Group. A Leadless Intracardiac Transcatheter Pacing System. N Engl J Med. 2016 Feb 11;374(6):533-41. doi: 10.1056/NEJMoa1511643. Epub 2015 Nov 9.

Reference Type RESULT
PMID: 26551877 (View on PubMed)

Mitacchione G, Schiavone M, Gasperetti A, Arabia G, Breitenstein A, Cerini M, Palmisano P, Montemerlo E, Ziacchi M, Gulletta S, Salghetti F, Russo G, Monaco C, Mazzone P, Hofer D, Tundo F, Rovaris G, Russo AD, Biffi M, Pisano ECL, Chierchia GB, Della Bella P, de Asmundis C, Saguner AM, Tondo C, Forleo GB, Curnis A. Outcomes of leadless pacemaker implantation following transvenous lead extraction in high-volume referral centers: Real-world data from a large international registry. Heart Rhythm. 2023 Mar;20(3):395-404. doi: 10.1016/j.hrthm.2022.12.002. Epub 2022 Dec 7.

Reference Type DERIVED
PMID: 36496135 (View on PubMed)

Other Identifiers

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Hsacco2022

Identifier Type: -

Identifier Source: org_study_id